node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM174A | GLYATL3 | ENSP00000307954 | ENSP00000360240 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | Glycine N-acyltransferase-like protein 3; Catalyzes the conjugation of long-chain fatty acyl-CoA thioester and glycine to produce long-chain N-(fatty acyl)glycine, an intermediate in the primary fatty acid amide biosynthetic pathway. | 0.471 |
FAM174A | HEATR5B | ENSP00000307954 | ENSP00000233099 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | HEAT repeat containing 5B; Belongs to the HEATR5 family. | 0.456 |
FAM174A | LIX1 | ENSP00000307954 | ENSP00000274382 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family. | 0.437 |
FAM174A | OR10V1 | ENSP00000307954 | ENSP00000302199 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | Olfactory receptor 10V1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.447 |
FAM174A | RGMB | ENSP00000307954 | ENSP00000308219 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | RGM domain family member B; Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. | 0.446 |
FAM174A | RIOK2 | ENSP00000307954 | ENSP00000283109 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | Serine/threonine-protein kinase RIO2; Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre- rRNA to the mature 18S rRNA. Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function. | 0.527 |
FAM174A | SEZ6L | ENSP00000307954 | ENSP00000248933 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons. | 0.474 |
FAM174A | ST8SIA4 | ENSP00000307954 | ENSP00000231461 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. | 0.514 |
FAM174A | TMEM168 | ENSP00000307954 | ENSP00000323068 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | Transmembrane protein 168; Belongs to the TMEM168 family. | 0.533 |
FAM174A | VSIG10 | ENSP00000307954 | ENSP00000352172 | Membrane protein FAM174A; Family with sequence similarity 174 member A. | V-set and immunoglobulin domain containing 10. | 0.452 |
GLYATL3 | FAM174A | ENSP00000360240 | ENSP00000307954 | Glycine N-acyltransferase-like protein 3; Catalyzes the conjugation of long-chain fatty acyl-CoA thioester and glycine to produce long-chain N-(fatty acyl)glycine, an intermediate in the primary fatty acid amide biosynthetic pathway. | Membrane protein FAM174A; Family with sequence similarity 174 member A. | 0.471 |
GLYATL3 | HEATR5B | ENSP00000360240 | ENSP00000233099 | Glycine N-acyltransferase-like protein 3; Catalyzes the conjugation of long-chain fatty acyl-CoA thioester and glycine to produce long-chain N-(fatty acyl)glycine, an intermediate in the primary fatty acid amide biosynthetic pathway. | HEAT repeat containing 5B; Belongs to the HEATR5 family. | 0.453 |
GLYATL3 | VSIG10 | ENSP00000360240 | ENSP00000352172 | Glycine N-acyltransferase-like protein 3; Catalyzes the conjugation of long-chain fatty acyl-CoA thioester and glycine to produce long-chain N-(fatty acyl)glycine, an intermediate in the primary fatty acid amide biosynthetic pathway. | V-set and immunoglobulin domain containing 10. | 0.410 |
HEATR5B | FAM174A | ENSP00000233099 | ENSP00000307954 | HEAT repeat containing 5B; Belongs to the HEATR5 family. | Membrane protein FAM174A; Family with sequence similarity 174 member A. | 0.456 |
HEATR5B | GLYATL3 | ENSP00000233099 | ENSP00000360240 | HEAT repeat containing 5B; Belongs to the HEATR5 family. | Glycine N-acyltransferase-like protein 3; Catalyzes the conjugation of long-chain fatty acyl-CoA thioester and glycine to produce long-chain N-(fatty acyl)glycine, an intermediate in the primary fatty acid amide biosynthetic pathway. | 0.453 |
HEATR5B | VSIG10 | ENSP00000233099 | ENSP00000352172 | HEAT repeat containing 5B; Belongs to the HEATR5 family. | V-set and immunoglobulin domain containing 10. | 0.433 |
LIX1 | FAM174A | ENSP00000274382 | ENSP00000307954 | Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family. | Membrane protein FAM174A; Family with sequence similarity 174 member A. | 0.437 |
LIX1 | RIOK2 | ENSP00000274382 | ENSP00000283109 | Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family. | Serine/threonine-protein kinase RIO2; Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre- rRNA to the mature 18S rRNA. Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function. | 0.582 |
OR10V1 | FAM174A | ENSP00000302199 | ENSP00000307954 | Olfactory receptor 10V1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Membrane protein FAM174A; Family with sequence similarity 174 member A. | 0.447 |
RGMB | FAM174A | ENSP00000308219 | ENSP00000307954 | RGM domain family member B; Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. | Membrane protein FAM174A; Family with sequence similarity 174 member A. | 0.446 |