STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR152Probable G-protein coupled receptor 152; Orphan receptor. (470 aa)    
Predicted Functional Partners:
GLIS3
Zinc finger protein GLIS3; Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).
    
 
 0.802
GPR108
G protein-coupled receptor 108.
      
 0.631
GPR171
Probable G-protein coupled receptor 171; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.578
PPP1R26
Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation.
    
 
 0.550
GPR89B
G protein-coupled receptor 89B.
      
 0.531
GPR162
Probable G-protein coupled receptor 162; Orphan receptor.
    
 
 0.526
GPR158
Probable G-protein coupled receptor 158; Orphan receptor; Belongs to the G-protein coupled receptor 3 family.
      
 0.524
GPR148
Probable G-protein coupled receptor 148; Orphan receptor.
      
 0.514
GPR89A
Golgi pH regulator A; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance; Belongs to the Golgi pH regulator (TC 1.A.38) family.
      
 0.508
PTRH1
peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family.
    
 
 0.502
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.