STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LY6G6CLymphocyte antigen 6 family member G6C. (125 aa)    
Predicted Functional Partners:
LY6G5C
Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation.
   
  
 0.796
LY6G6D
Lymphocyte antigen 6 family member G6D.
   
 
 0.762
LY6G6E
Lymphocyte antigen 6 family member G6E.
   
  
 0.720
LY6G5B
Lymphocyte antigen 6 family member G5B.
   
  
 0.696
LY6G6F
Lymphocyte antigen 6 complex locus protein G6f; May play a role in the downstream signal transduction pathways involving GRB2 and GRB7.
   
  
 0.669
LY6L
Lymphocyte antigen 6 family member L.
      
 0.603
PATE3
Prostate and testis expressed 3; Belongs to the PATE family.
      
 0.593
MPIG6B
Megakaryocyte and platelet inhibitory receptor G6b; Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production. Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling. Appears to operate in a calcium-independent manner.
   
  
 0.587
VWA7
Von Willebrand factor A domain containing 7.
   
  
 0.576
PINLYP
Phospholipase A2 inhibitor and LY6/PLAUR domain containing; Belongs to the CNF-like-inhibitor family.
      
 0.571
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.