node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BASP1 | CALM3 | ENSP00000319281 | ENSP00000291295 | Brain abundant membrane attached signal protein 1; Belongs to the BASP1 family. | Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. | 0.604 |
BASP1 | CALML3 | ENSP00000319281 | ENSP00000315299 | Brain abundant membrane attached signal protein 1; Belongs to the BASP1 family. | Calmodulin-like protein 3; May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates. | 0.736 |
BASP1 | CALML4 | ENSP00000319281 | ENSP00000419081 | Brain abundant membrane attached signal protein 1; Belongs to the BASP1 family. | Calmodulin-like protein 4; Calmodulin like 4; Belongs to the calmodulin family. | 0.744 |
BASP1 | CALML5 | ENSP00000319281 | ENSP00000369689 | Brain abundant membrane attached signal protein 1; Belongs to the BASP1 family. | Calmodulin-like protein 5; Binds calcium. May be involved in terminal differentiation of keratinocytes. | 0.736 |
BASP1 | CALML6 | ENSP00000319281 | ENSP00000304643 | Brain abundant membrane attached signal protein 1; Belongs to the BASP1 family. | Calmodulin-like protein 6; Calmodulin like 6; Belongs to the calmodulin family. Calglandulin subfamily. | 0.745 |
BASP1 | MARCKS | ENSP00000319281 | ENSP00000478061 | Brain abundant membrane attached signal protein 1; Belongs to the BASP1 family. | Myristoylated alanine-rich C-kinase substrate; MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. | 0.946 |
BASP1 | MARCKSL1 | ENSP00000319281 | ENSP00000362638 | Brain abundant membrane attached signal protein 1; Belongs to the BASP1 family. | MARCKS-related protein; Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity). | 0.577 |
CALM1 | CALM2 | ENSP00000499717 | ENSP00000499797 | Calmodulin-1; Calmodulin 1; Belongs to the calmodulin family. | Calmodulin 2. | 0.939 |
CALM1 | CALM3 | ENSP00000499717 | ENSP00000291295 | Calmodulin-1; Calmodulin 1; Belongs to the calmodulin family. | Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. | 0.931 |
CALM1 | MARCKS | ENSP00000499717 | ENSP00000478061 | Calmodulin-1; Calmodulin 1; Belongs to the calmodulin family. | Myristoylated alanine-rich C-kinase substrate; MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. | 0.935 |
CALM1 | PRKCD | ENSP00000499717 | ENSP00000331602 | Calmodulin-1; Calmodulin 1; Belongs to the calmodulin family. | Protein kinase C delta type regulatory subunit; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Nega [...] | 0.577 |
CALM2 | CALM1 | ENSP00000499797 | ENSP00000499717 | Calmodulin 2. | Calmodulin-1; Calmodulin 1; Belongs to the calmodulin family. | 0.939 |
CALM2 | CALM3 | ENSP00000499797 | ENSP00000291295 | Calmodulin 2. | Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. | 0.959 |
CALM2 | CALML3 | ENSP00000499797 | ENSP00000315299 | Calmodulin 2. | Calmodulin-like protein 3; May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates. | 0.571 |
CALM2 | CALML4 | ENSP00000499797 | ENSP00000419081 | Calmodulin 2. | Calmodulin-like protein 4; Calmodulin like 4; Belongs to the calmodulin family. | 0.497 |
CALM2 | CALML5 | ENSP00000499797 | ENSP00000369689 | Calmodulin 2. | Calmodulin-like protein 5; Binds calcium. May be involved in terminal differentiation of keratinocytes. | 0.500 |
CALM2 | CALML6 | ENSP00000499797 | ENSP00000304643 | Calmodulin 2. | Calmodulin-like protein 6; Calmodulin like 6; Belongs to the calmodulin family. Calglandulin subfamily. | 0.489 |
CALM2 | MARCKS | ENSP00000499797 | ENSP00000478061 | Calmodulin 2. | Myristoylated alanine-rich C-kinase substrate; MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. | 0.960 |
CALM3 | BASP1 | ENSP00000291295 | ENSP00000319281 | Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. | Brain abundant membrane attached signal protein 1; Belongs to the BASP1 family. | 0.604 |
CALM3 | CALM1 | ENSP00000291295 | ENSP00000499717 | Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. | Calmodulin-1; Calmodulin 1; Belongs to the calmodulin family. | 0.931 |