node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATOX1 | ATP7B | ENSP00000430598 | ENSP00000242839 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense; Belongs to the ATX1 family. | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | 0.998 |
ATOX1 | MT1E | ENSP00000430598 | ENSP00000328137 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense; Belongs to the ATX1 family. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.668 |
ATOX1 | MT3 | ENSP00000430598 | ENSP00000200691 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense; Belongs to the ATX1 family. | Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. | 0.432 |
ATOX1 | MT4 | ENSP00000430598 | ENSP00000219162 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense; Belongs to the ATX1 family. | Metallothionein-4; Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia. | 0.426 |
ATOX1 | SLC30A1 | ENSP00000430598 | ENSP00000355968 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense; Belongs to the ATX1 family. | Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.503 |
ATP7B | ATOX1 | ENSP00000242839 | ENSP00000430598 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense; Belongs to the ATX1 family. | 0.998 |
ATP7B | MT1E | ENSP00000242839 | ENSP00000328137 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.823 |
ATP7B | MT3 | ENSP00000242839 | ENSP00000200691 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. | 0.423 |
ATP7B | MT4 | ENSP00000242839 | ENSP00000219162 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Metallothionein-4; Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia. | 0.442 |
ATP7B | SLC30A1 | ENSP00000242839 | ENSP00000355968 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.581 |
KRT13 | KRT33A | ENSP00000246635 | ENSP00000007735 | Keratin, type I cytoskeletal 13; Keratin 13. | Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family. | 0.437 |
KRT13 | KRT4 | ENSP00000246635 | ENSP00000448220 | Keratin, type I cytoskeletal 13; Keratin 13. | Keratin, type II cytoskeletal 4; Keratin 4; Belongs to the intermediate filament family. | 0.986 |
KRT13 | MT1E | ENSP00000246635 | ENSP00000328137 | Keratin, type I cytoskeletal 13; Keratin 13. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.584 |
KRT13 | MT4 | ENSP00000246635 | ENSP00000219162 | Keratin, type I cytoskeletal 13; Keratin 13. | Metallothionein-4; Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia. | 0.485 |
KRT33A | KRT13 | ENSP00000007735 | ENSP00000246635 | Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family. | Keratin, type I cytoskeletal 13; Keratin 13. | 0.437 |
KRT33A | KRT4 | ENSP00000007735 | ENSP00000448220 | Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 4; Keratin 4; Belongs to the intermediate filament family. | 0.614 |
KRT33A | MT1E | ENSP00000007735 | ENSP00000328137 | Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.557 |
KRT33A | MT4 | ENSP00000007735 | ENSP00000219162 | Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family. | Metallothionein-4; Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia. | 0.501 |
KRT4 | KRT13 | ENSP00000448220 | ENSP00000246635 | Keratin, type II cytoskeletal 4; Keratin 4; Belongs to the intermediate filament family. | Keratin, type I cytoskeletal 13; Keratin 13. | 0.986 |
KRT4 | KRT33A | ENSP00000448220 | ENSP00000007735 | Keratin, type II cytoskeletal 4; Keratin 4; Belongs to the intermediate filament family. | Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family. | 0.614 |