node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C5orf24 | PBX1 | ENSP00000378427 | ENSP00000405890 | UPF0461 protein C5orf24; Chromosome 5 open reading frame 24; Belongs to the UPF0461 family. | Pre-B-cell leukemia transcription factor 1; Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhanc [...] | 0.420 |
C5orf24 | PKNOX2 | ENSP00000378427 | ENSP00000298282 | UPF0461 protein C5orf24; Chromosome 5 open reading frame 24; Belongs to the UPF0461 family. | Homeobox protein PKNOX2; PBX/knotted 1 homeobox 2; Belongs to the TALE/MEIS homeobox family. | 0.591 |
DDX25 | HYLS1 | ENSP00000263576 | ENSP00000414884 | ATP-dependent RNA helicase DDX25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity). | Hydrolethalus syndrome protein 1; Plays a role in ciliogenesis. | 0.943 |
DDX25 | PKNOX2 | ENSP00000263576 | ENSP00000298282 | ATP-dependent RNA helicase DDX25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity). | Homeobox protein PKNOX2; PBX/knotted 1 homeobox 2; Belongs to the TALE/MEIS homeobox family. | 0.908 |
HOXB1 | HOXB2 | ENSP00000355140 | ENSP00000331741 | Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. | Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily. | 0.750 |
HOXB1 | PBX1 | ENSP00000355140 | ENSP00000405890 | Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. | Pre-B-cell leukemia transcription factor 1; Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhanc [...] | 0.999 |
HOXB1 | PBX2 | ENSP00000355140 | ENSP00000364190 | Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. | Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1. | 0.628 |
HOXB1 | PBX3 | ENSP00000355140 | ENSP00000362588 | Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. | Pre-B-cell leukemia transcription factor 3; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. | 0.553 |
HOXB1 | PBX4 | ENSP00000355140 | ENSP00000251203 | Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. | Pre-B-cell leukemia transcription factor 4; PBX homeobox 4; Belongs to the TALE/PBX homeobox family. | 0.556 |
HOXB1 | PKNOX2 | ENSP00000355140 | ENSP00000298282 | Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. | Homeobox protein PKNOX2; PBX/knotted 1 homeobox 2; Belongs to the TALE/MEIS homeobox family. | 0.776 |
HOXB2 | HOXB1 | ENSP00000331741 | ENSP00000355140 | Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily. | Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. | 0.750 |
HOXB2 | PBX1 | ENSP00000331741 | ENSP00000405890 | Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily. | Pre-B-cell leukemia transcription factor 1; Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhanc [...] | 0.854 |
HOXB2 | PBX2 | ENSP00000331741 | ENSP00000364190 | Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily. | Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1. | 0.499 |
HOXB2 | PBX3 | ENSP00000331741 | ENSP00000362588 | Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily. | Pre-B-cell leukemia transcription factor 3; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. | 0.551 |
HOXB2 | PBX4 | ENSP00000331741 | ENSP00000251203 | Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily. | Pre-B-cell leukemia transcription factor 4; PBX homeobox 4; Belongs to the TALE/PBX homeobox family. | 0.453 |
HOXB2 | PKNOX2 | ENSP00000331741 | ENSP00000298282 | Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily. | Homeobox protein PKNOX2; PBX/knotted 1 homeobox 2; Belongs to the TALE/MEIS homeobox family. | 0.773 |
HYLS1 | DDX25 | ENSP00000414884 | ENSP00000263576 | Hydrolethalus syndrome protein 1; Plays a role in ciliogenesis. | ATP-dependent RNA helicase DDX25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity). | 0.943 |
HYLS1 | PKNOX2 | ENSP00000414884 | ENSP00000298282 | Hydrolethalus syndrome protein 1; Plays a role in ciliogenesis. | Homeobox protein PKNOX2; PBX/knotted 1 homeobox 2; Belongs to the TALE/MEIS homeobox family. | 0.907 |
LMX1B | PBX1 | ENSP00000347684 | ENSP00000405890 | LIM homeobox transcription factor 1-beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. | Pre-B-cell leukemia transcription factor 1; Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhanc [...] | 0.830 |
LMX1B | PBX2 | ENSP00000347684 | ENSP00000364190 | LIM homeobox transcription factor 1-beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. | Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1. | 0.759 |