Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMER3 | PLEKHB2 | ENSP00000392700 | ENSP00000385892 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | 0.454 |
ATP8A1 | PLEKHB2 | ENSP00000371084 | ENSP00000385892 | Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...] | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | 0.541 |
CELF4 | PLEKHB2 | ENSP00000410584 | ENSP00000385892 | CUGBP Elav-like family member 4; RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre- mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic site [...] | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | 0.608 |
NPIPA7 | PLEKHB2 | ENSP00000431814 | ENSP00000385892 | Nuclear pore complex interacting protein family member A7. | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | 0.435 |
PLEK | PLEKHB2 | ENSP00000234313 | ENSP00000385892 | Pleckstrin; Major protein kinase C substrate of platelets. | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | 0.599 |
PLEK2 | PLEKHB2 | ENSP00000216446 | ENSP00000385892 | Pleckstrin-2; May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation. | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | 0.602 |
PLEKHB2 | AMER3 | ENSP00000385892 | ENSP00000392700 | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). | 0.454 |
PLEKHB2 | ATP8A1 | ENSP00000385892 | ENSP00000371084 | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in r [...] | 0.541 |
PLEKHB2 | CELF4 | ENSP00000385892 | ENSP00000410584 | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | CUGBP Elav-like family member 4; RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre- mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic site [...] | 0.608 |
PLEKHB2 | NPIPA7 | ENSP00000385892 | ENSP00000431814 | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | Nuclear pore complex interacting protein family member A7. | 0.435 |
PLEKHB2 | PLEK | ENSP00000385892 | ENSP00000234313 | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | Pleckstrin; Major protein kinase C substrate of platelets. | 0.599 |
PLEKHB2 | PLEK2 | ENSP00000385892 | ENSP00000216446 | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | Pleckstrin-2; May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation. | 0.602 |
PLEKHB2 | TMEM231 | ENSP00000385892 | ENSP00000258173 | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | Transmembrane protein 231; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). | 0.422 |
TMEM231 | PLEKHB2 | ENSP00000258173 | ENSP00000385892 | Transmembrane protein 231; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. | 0.422 |