node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C18orf21 | PNMA6A | ENSP00000465517 | ENSP00000391488 | UPF0711 protein C18orf21; Chromosome 18 open reading frame 21. | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 0.479 |
DAP3 | PNMA6A | ENSP00000357320 | ENSP00000391488 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family. | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 0.494 |
ENSP00000498408 | PNMA6A | ENSP00000498408 | ENSP00000391488 | Uncharacterized protein. | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 0.531 |
HLA-DRB5 | PNMA6A | ENSP00000364114 | ENSP00000391488 | HLA class II histocompatibility antigen, DR beta 5 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for pr [...] | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 0.487 |
MOAP1 | PNMA1 | ENSP00000451594 | ENSP00000318914 | Modulator of apoptosis 1; Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation; Belongs to the PNMA family. | Paraneoplastic antigen Ma1; PNMA family member 1; Belongs to the PNMA family. | 0.797 |
MOAP1 | PNMA6A | ENSP00000451594 | ENSP00000391488 | Modulator of apoptosis 1; Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation; Belongs to the PNMA family. | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 0.669 |
NPIPA7 | PNMA6A | ENSP00000431814 | ENSP00000391488 | Nuclear pore complex interacting protein family member A7. | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 0.566 |
NPIPA8 | PNMA6A | ENSP00000435325 | ENSP00000391488 | Nuclear pore complex interacting protein family member A8. | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 0.566 |
PNMA1 | MOAP1 | ENSP00000318914 | ENSP00000451594 | Paraneoplastic antigen Ma1; PNMA family member 1; Belongs to the PNMA family. | Modulator of apoptosis 1; Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation; Belongs to the PNMA family. | 0.797 |
PNMA1 | PNMA6A | ENSP00000318914 | ENSP00000391488 | Paraneoplastic antigen Ma1; PNMA family member 1; Belongs to the PNMA family. | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 0.743 |
PNMA1 | RTL6 | ENSP00000318914 | ENSP00000340434 | Paraneoplastic antigen Ma1; PNMA family member 1; Belongs to the PNMA family. | Retrotransposon Gag like 6. | 0.462 |
PNMA6A | C18orf21 | ENSP00000391488 | ENSP00000465517 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | UPF0711 protein C18orf21; Chromosome 18 open reading frame 21. | 0.479 |
PNMA6A | DAP3 | ENSP00000391488 | ENSP00000357320 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family. | 0.494 |
PNMA6A | ENSP00000498408 | ENSP00000391488 | ENSP00000498408 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | Uncharacterized protein. | 0.531 |
PNMA6A | HLA-DRB5 | ENSP00000391488 | ENSP00000364114 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | HLA class II histocompatibility antigen, DR beta 5 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for pr [...] | 0.487 |
PNMA6A | MOAP1 | ENSP00000391488 | ENSP00000451594 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | Modulator of apoptosis 1; Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation; Belongs to the PNMA family. | 0.669 |
PNMA6A | NPIPA7 | ENSP00000391488 | ENSP00000431814 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | Nuclear pore complex interacting protein family member A7. | 0.566 |
PNMA6A | NPIPA8 | ENSP00000391488 | ENSP00000435325 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | Nuclear pore complex interacting protein family member A8. | 0.566 |
PNMA6A | PNMA1 | ENSP00000391488 | ENSP00000318914 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | Paraneoplastic antigen Ma1; PNMA family member 1; Belongs to the PNMA family. | 0.743 |
PNMA6A | PRDX3 | ENSP00000391488 | ENSP00000298510 | Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family. | Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. | 0.510 |