node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAT3 | SCAMP4 | ENSP00000332448 | ENSP00000316007 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | 0.446 |
DUS3L | REXO1 | ENSP00000311977 | ENSP00000170168 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the Dus family. Dus3 subfamily. | RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro; Belongs to the REXO1/REXO3 family. | 0.456 |
DUS3L | SCAMP4 | ENSP00000311977 | ENSP00000316007 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the Dus family. Dus3 subfamily. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | 0.412 |
FAM174B | SCAMP4 | ENSP00000329040 | ENSP00000316007 | Membrane protein FAM174B; Essential for Golgi structural integrity. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | 0.477 |
FAM174B | XXYLT1 | ENSP00000329040 | ENSP00000309640 | Membrane protein FAM174B; Essential for Golgi structural integrity. | Xyloside xylosyltransferase 1; Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose. Known targets include Notch proteins and coagulation factors, such as F9 ; Belongs to the glycosyltransferase 8 family. | 0.444 |
GDPD5 | SCAMP4 | ENSP00000337972 | ENSP00000316007 | Glycerophosphodiester phosphodiesterase domain-containing protein 5; Glycerophosphodiester phosphodiesterase that promotes neurite formation and drives spinal motor neuron differentiation (By similarity). Mediates the cleavage of glycosylphosphatidylinositol (GPI) anchor of target proteins: removes the GPI-anchor of RECK, leading to release RECK from the plasma membrane (By similarity). May contribute to the osmotic regulation of cellular glycerophosphocholine (By similarity). | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | 0.453 |
POMT2 | SCAMP4 | ENSP00000261534 | ENSP00000316007 | Protein O-mannosyl-transferase 2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. Belongs to the glycosyltransferase 39 family. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | 0.459 |
REEP5 | SCAMP4 | ENSP00000368959 | ENSP00000316007 | Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors; Belongs to the DP1 family. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | 0.459 |
REXO1 | DUS3L | ENSP00000170168 | ENSP00000311977 | RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro; Belongs to the REXO1/REXO3 family. | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the Dus family. Dus3 subfamily. | 0.456 |
REXO1 | SCAMP4 | ENSP00000170168 | ENSP00000316007 | RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro; Belongs to the REXO1/REXO3 family. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | 0.421 |
SCAMP4 | ADAT3 | ENSP00000316007 | ENSP00000332448 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | 0.446 |
SCAMP4 | DUS3L | ENSP00000316007 | ENSP00000311977 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the Dus family. Dus3 subfamily. | 0.412 |
SCAMP4 | FAM174B | ENSP00000316007 | ENSP00000329040 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | Membrane protein FAM174B; Essential for Golgi structural integrity. | 0.477 |
SCAMP4 | GDPD5 | ENSP00000316007 | ENSP00000337972 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | Glycerophosphodiester phosphodiesterase domain-containing protein 5; Glycerophosphodiester phosphodiesterase that promotes neurite formation and drives spinal motor neuron differentiation (By similarity). Mediates the cleavage of glycosylphosphatidylinositol (GPI) anchor of target proteins: removes the GPI-anchor of RECK, leading to release RECK from the plasma membrane (By similarity). May contribute to the osmotic regulation of cellular glycerophosphocholine (By similarity). | 0.453 |
SCAMP4 | POMT2 | ENSP00000316007 | ENSP00000261534 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | Protein O-mannosyl-transferase 2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. Belongs to the glycosyltransferase 39 family. | 0.459 |
SCAMP4 | REEP5 | ENSP00000316007 | ENSP00000368959 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors; Belongs to the DP1 family. | 0.459 |
SCAMP4 | REXO1 | ENSP00000316007 | ENSP00000170168 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro; Belongs to the REXO1/REXO3 family. | 0.421 |
SCAMP4 | SH3GL1 | ENSP00000316007 | ENSP00000269886 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | Endophilin-A2; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity); Belongs to the endophilin family. | 0.541 |
SCAMP4 | XXYLT1 | ENSP00000316007 | ENSP00000309640 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | Xyloside xylosyltransferase 1; Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose. Known targets include Notch proteins and coagulation factors, such as F9 ; Belongs to the glycosyltransferase 8 family. | 0.464 |
SH3GL1 | SCAMP4 | ENSP00000269886 | ENSP00000316007 | Endophilin-A2; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity); Belongs to the endophilin family. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. | 0.541 |