node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CFAP45 | CFAP53 | ENSP00000357079 | ENSP00000381553 | Cilia and flagella associated protein 45. | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | 0.880 |
CFAP45 | EFHC1 | ENSP00000357079 | ENSP00000360107 | Cilia and flagella associated protein 45. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.912 |
CFAP45 | EFHC2 | ENSP00000357079 | ENSP00000404232 | Cilia and flagella associated protein 45. | EF-hand domain-containing family member C2; EF-hand domain containing 2. | 0.909 |
CFAP45 | PACRG | ENSP00000357079 | ENSP00000337946 | Cilia and flagella associated protein 45. | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. | 0.895 |
CFAP45 | RIBC2 | ENSP00000357079 | ENSP00000483356 | Cilia and flagella associated protein 45. | RIB43A domain with coiled-coils 2. | 0.866 |
CFAP45 | TEKT1 | ENSP00000357079 | ENSP00000341346 | Cilia and flagella associated protein 45. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family. | 0.902 |
CFAP45 | TEKT2 | ENSP00000357079 | ENSP00000207457 | Cilia and flagella associated protein 45. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. | 0.905 |
CFAP45 | TEKT3 | ENSP00000357079 | ENSP00000379263 | Cilia and flagella associated protein 45. | Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility. | 0.860 |
CFAP45 | TEKT4 | ENSP00000357079 | ENSP00000295201 | Cilia and flagella associated protein 45. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family. | 0.842 |
CFAP53 | CFAP45 | ENSP00000381553 | ENSP00000357079 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | Cilia and flagella associated protein 45. | 0.880 |
CFAP53 | EFHC1 | ENSP00000381553 | ENSP00000360107 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.835 |
CFAP53 | EFHC2 | ENSP00000381553 | ENSP00000404232 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | EF-hand domain-containing family member C2; EF-hand domain containing 2. | 0.880 |
CFAP53 | PACRG | ENSP00000381553 | ENSP00000337946 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. | 0.832 |
CFAP53 | RIBC2 | ENSP00000381553 | ENSP00000483356 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | RIB43A domain with coiled-coils 2. | 0.830 |
CFAP53 | TEKT1 | ENSP00000381553 | ENSP00000341346 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family. | 0.849 |
CFAP53 | TEKT2 | ENSP00000381553 | ENSP00000207457 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. | 0.888 |
CFAP53 | TEKT3 | ENSP00000381553 | ENSP00000379263 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility. | 0.885 |
CFAP53 | TEKT4 | ENSP00000381553 | ENSP00000295201 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family. | 0.830 |
EFHC1 | CFAP45 | ENSP00000360107 | ENSP00000357079 | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | Cilia and flagella associated protein 45. | 0.912 |
EFHC1 | CFAP53 | ENSP00000360107 | ENSP00000381553 | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | 0.835 |