node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C9orf116 | CFAP126 | ENSP00000395281 | ENSP00000356951 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | 0.860 |
C9orf116 | CFAP52 | ENSP00000395281 | ENSP00000339449 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | 0.838 |
C9orf116 | EFHC1 | ENSP00000395281 | ENSP00000360107 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.854 |
C9orf116 | EFHC2 | ENSP00000395281 | ENSP00000404232 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | EF-hand domain-containing family member C2; EF-hand domain containing 2. | 0.875 |
C9orf116 | FAM183A | ENSP00000395281 | ENSP00000334415 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Protein FAM183A; Family with sequence similarity 183 member A; Belongs to the FAM183 family. | 0.810 |
C9orf116 | TEKT1 | ENSP00000395281 | ENSP00000341346 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family. | 0.942 |
C9orf116 | TEKT2 | ENSP00000395281 | ENSP00000207457 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. | 0.849 |
C9orf116 | TEKT3 | ENSP00000395281 | ENSP00000379263 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility. | 0.862 |
C9orf116 | TEKT4 | ENSP00000395281 | ENSP00000295201 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family. | 0.859 |
C9orf116 | TUBB4B | ENSP00000395281 | ENSP00000341289 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. | 0.830 |
CFAP126 | C9orf116 | ENSP00000356951 | ENSP00000395281 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | 0.860 |
CFAP126 | CFAP52 | ENSP00000356951 | ENSP00000339449 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | 0.898 |
CFAP126 | EFHC1 | ENSP00000356951 | ENSP00000360107 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.868 |
CFAP126 | EFHC2 | ENSP00000356951 | ENSP00000404232 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | EF-hand domain-containing family member C2; EF-hand domain containing 2. | 0.855 |
CFAP126 | FAM183A | ENSP00000356951 | ENSP00000334415 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | Protein FAM183A; Family with sequence similarity 183 member A; Belongs to the FAM183 family. | 0.819 |
CFAP126 | TEKT1 | ENSP00000356951 | ENSP00000341346 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family. | 0.963 |
CFAP126 | TEKT2 | ENSP00000356951 | ENSP00000207457 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. | 0.847 |
CFAP126 | TEKT3 | ENSP00000356951 | ENSP00000379263 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility. | 0.844 |
CFAP126 | TEKT4 | ENSP00000356951 | ENSP00000295201 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family. | 0.862 |
CFAP126 | TUBB4B | ENSP00000356951 | ENSP00000341289 | Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. | Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. | 0.826 |