TMEM39B protein (human) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

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Score

TMEM39B

Transmembrane protein 39B; Belongs to the TMEM39 family. (492 aa)

Predicted Functional Partners:

FAM118A

0.525

REEP6

0.427

DNAJC18

0.415

RHBDD3

0.403

GPR137C

0.401

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNAJC18	FAM118A	ENSP00000302843	ENSP00000216214	DnaJ heat shock protein family member C18.	Protein FAM118A; Family with sequence similarity 118 member A.	0.527
DNAJC18	REEP6	ENSP00000302843	ENSP00000233596	DnaJ heat shock protein family member C18.	Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).	0.440
DNAJC18	RHBDD3	ENSP00000302843	ENSP00000216085	DnaJ heat shock protein family member C18.	Rhomboid domain containing 3.	0.423
DNAJC18	TMEM39B	ENSP00000302843	ENSP00000338165	DnaJ heat shock protein family member C18.	Transmembrane protein 39B; Belongs to the TMEM39 family.	0.415
FAM118A	DNAJC18	ENSP00000216214	ENSP00000302843	Protein FAM118A; Family with sequence similarity 118 member A.	DnaJ heat shock protein family member C18.	0.527
FAM118A	REEP6	ENSP00000216214	ENSP00000233596	Protein FAM118A; Family with sequence similarity 118 member A.	Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).	0.466
FAM118A	RHBDD3	ENSP00000216214	ENSP00000216085	Protein FAM118A; Family with sequence similarity 118 member A.	Rhomboid domain containing 3.	0.508
FAM118A	TMEM39B	ENSP00000216214	ENSP00000338165	Protein FAM118A; Family with sequence similarity 118 member A.	Transmembrane protein 39B; Belongs to the TMEM39 family.	0.525
GPR137C	TMEM39B	ENSP00000315106	ENSP00000338165	Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family.	Transmembrane protein 39B; Belongs to the TMEM39 family.	0.401
REEP6	DNAJC18	ENSP00000233596	ENSP00000302843	Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).	DnaJ heat shock protein family member C18.	0.440
REEP6	FAM118A	ENSP00000233596	ENSP00000216214	Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).	Protein FAM118A; Family with sequence similarity 118 member A.	0.466
REEP6	RHBDD3	ENSP00000233596	ENSP00000216085	Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).	Rhomboid domain containing 3.	0.445
REEP6	TMEM39B	ENSP00000233596	ENSP00000338165	Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).	Transmembrane protein 39B; Belongs to the TMEM39 family.	0.427
RHBDD3	DNAJC18	ENSP00000216085	ENSP00000302843	Rhomboid domain containing 3.	DnaJ heat shock protein family member C18.	0.423
RHBDD3	FAM118A	ENSP00000216085	ENSP00000216214	Rhomboid domain containing 3.	Protein FAM118A; Family with sequence similarity 118 member A.	0.508
RHBDD3	REEP6	ENSP00000216085	ENSP00000233596	Rhomboid domain containing 3.	Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).	0.445
RHBDD3	TMEM39B	ENSP00000216085	ENSP00000338165	Rhomboid domain containing 3.	Transmembrane protein 39B; Belongs to the TMEM39 family.	0.403
TMEM39B	DNAJC18	ENSP00000338165	ENSP00000302843	Transmembrane protein 39B; Belongs to the TMEM39 family.	DnaJ heat shock protein family member C18.	0.415
TMEM39B	FAM118A	ENSP00000338165	ENSP00000216214	Transmembrane protein 39B; Belongs to the TMEM39 family.	Protein FAM118A; Family with sequence similarity 118 member A.	0.525
TMEM39B	GPR137C	ENSP00000338165	ENSP00000315106	Transmembrane protein 39B; Belongs to the TMEM39 family.	Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family.	0.401