searching ... STRING: functional protein association networks

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The following proteins in Mus musculus appear to match your input.
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101 query items

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1) '10090.ENSMUSP00000032200':

Slc6a12 - Sodium- and chloride-dependent betaine transporter; Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation (By similarity); Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily. [a.k.a. GAT-2, XM_006505535.2, ENSMUSG00000030109]

2) '10090.ENSMUSP00000096677':

Arfgef2 - Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. Involved in the regulation of Golgi vesicular transport. Required for the integrity of the endosomal compartment. Involved in trafficking from the trans-Golgi network (TGN) to endosomes and is required for membrane association of the AP-1 complex and GGA1. Seems to be involved in recycling of the transferrin receptor from recycling endosomes to the plasma [...] [a.k.a. XM_006500483, CCDS38335.1, XP_030108138]

3) '10090.ENSMUSP00000023344':

Slc35a5 - Probable UDP-sugar transporter protein SLC35A5. [a.k.a. mmu:74102, Slc35a5-206, BAC27026.1]

4) '10090.ENSMUSP00000124028':

4933434E20Rik - Uncharacterized protein C1orf43 homolog. [a.k.a. ENSMUST00000162390, UPI0000027B6B, NP_081776]

5) '10090.ENSMUSP00000130195':

St13 - Hsc70-interacting protein; One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity). [a.k.a. BAE27237.1, E9Q1X9, ENSMUSP00000130195]

6) '10090.ENSMUSP00000072803':

Ugt1a1 - UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. [a.k.a. UDPGT 1-1, Glucuronosyltransferase, R-MMU-156580]

7) '10090.ENSMUSP00000114026':

Lrp3 - Low density lipoprotein receptor-related protein 3. [a.k.a. ENSMUST00000155404, NM_001024707.2, XP_006540228]

8) '10090.ENSMUSP00000085986':

Arfgef1 - Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent of its GEF activity. Required for the maturaion of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and [...] [a.k.a. Q8BKL2, UPI000198D188, Arfgef1-202]

9) '10090.ENSMUSP00000038331':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

10) '10090.ENSMUSP00000121751':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

11) '10090.ENSMUSP00000033723':

Syap1 - Synapse-associated protein 1; Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation. [a.k.a. Q9D870, NM_025932, AW011796]

12) '10090.ENSMUSP00000097792':

Dolk - Dolichol kinase; Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. [a.k.a. 227697, R-MMU-392499, NP_808316]

13) '10090.ENSMUSP00000023749':

Tmbim6 - Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation. [a.k.a. ENSMUSP00000125563, Q9D2C7, uc007xpm.2]

14) '10090.ENSMUSP00000084541':

Foxd3 - Forkhead box protein D3; Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri- implantation stages of embryogenesis. [a.k.a. Forkhead box D3, NP_034555, Hfh2]

15) '10090.ENSMUSP00000027812':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

16) '10090.ENSMUSP00000072344':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

17) '10090.ENSMUSP00000029836':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

18) '10090.ENSMUSP00000090130':

Vps26a - Vacuolar protein sorting-associated protein 26A; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans- Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for carg [...] [a.k.a. NP_001106826.1, ENSMUST00000219574, ENSMUSG00000020078]

19) '10090.ENSMUSP00000112430':

Fgfr2 - Fibroblast growth factor receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell p [...] [a.k.a. Fgfr2-224, ENSMUSP00000112672, D6RJK5]

20) '10090.ENSMUSP00000037627':

Trp53inp2 - Tumor protein p53-inducible nuclear protein 2; Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. [a.k.a. BC043086, Trp53inp2-202, ENSMUSP00000037627]

101 query items

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