searching ... STRING: functional protein association networks

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The following proteins in Mus musculus appear to match your input.
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101 query items

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1) '10090.ENSMUSP00000048836':

C1qa - Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. [a.k.a. R-MMU-173623, BAE23115.1, MGI:88223]

2) '10090.ENSMUSP00000110126':

Il1rn - Interleukin-1 receptor antagonist protein; Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity; Belongs to the IL-1 family. [a.k.a. ENSMUSP00000110131, ENSMUSP00000141269, NP_112444]

3) '10090.ENSMUSP00000138771':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

4) '10090.ENSMUSP00000043956':

Iapp - Islet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family. [a.k.a. DAP, NP_034621, ENSMUSP00000043956]

5) '10090.ENSMUSP00000047431':

Tagap - T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein. May play a role in transmission ratio distortion (TRD) in mouse, in which heterozygous males for t-locus transmit their t-carrying chromosome to 95% or more of their offspring. [a.k.a. B2RWW0, Tcd-1, R-MMU-194840]

6) '10090.ENSMUSP00000063001':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

7) '10090.ENSMUSP00000038506':

Fstl5 - Follistatin-related protein 5. [a.k.a. Follistatin-related protein 5, 213262, NM_178673]

8) '10090.ENSMUSP00000042792':

Msl1 - Male-specific lethal 1 homolog; Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub) (By similarity). This modification in turn stimulates histone H3 methylation at 'Lys-5' (H3K4me) and 'Lys-80' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1 (By similarity). In the MSL complex, acts as a scaffold to [...] [a.k.a. ENSMUST00000107485.7, A3KFP2, BAB29868.1]

9) '10090.ENSMUSP00000055104':

Ticam1 - TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF- kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif [...] [a.k.a. TCAM1_MOUSE, AAH94338.1, TIR domain-containing adapter molecule 1]

10) '10090.ENSMUSP00000072231':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

11) '10090.ENSMUSP00000000500':

Pdgfb - Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] [a.k.a. PDGF subunit B, R-MMU-186797, NP_035187.2]

12) '10090.ENSMUSP00000130497':

Mc5r - Melanocortin receptor 5; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. [a.k.a. ENSMUSP00000130497, NM_013596, NP_038624.2]

13) '10090.ENSMUSP00000106845':

Ifi204 - Interferon-activable protein 204; Inhibits the transcription of ribosomal RNA. May inhibit DNA binding by UBTF. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways. Acts as a coactivator of RUNX2 during osteogenesis. May be involved in macrophage differentiation. Enables skeletal muscle and cardiac myocyte differentiation by sequestring Id proteins in the cytosol and promoting their ubiquitination and subsequent degradation. Belongs to the HIN-200 family. [a.k.a. ENSMUST00000111214, P0DOV2, 5Z7D]

14) '10090.ENSMUSP00000097435':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

15) '10090.ENSMUSP00000101690':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

16) '10090.ENSMUSP00000033602':

Tnmd - Tenomodulin; May be an angiogenesis inhibitor; Belongs to the chondromodulin-1 family. [a.k.a. ENSMUSG00000031250, Chondromodulin-1-like protein, ChM1L]

17) '10090.ENSMUSP00000027623':

Tsn - Translin; DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. Belongs to the translin family. [a.k.a. 1KEY, Component 3 of promoter of RISC, ENSMUST00000186608]

18) '10090.ENSMUSP00000129116':

Sis - Sucrase isomaltase (alpha-glucosidase). [a.k.a. R-MMU-189085, ENSMUSP00000129116, ENSMUST00000094190]

19) '10090.ENSMUSP00000110233':

Gm609 - Predicted gene 609. [a.k.a. ENSMUSP00000110233, Predicted gene 609, XM_011245855]

20) '10090.ENSMUSP00000093329':

Pkib - cAMP-dependent protein kinase inhibitor beta; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains; Belongs to the PKI family. [a.k.a. UPI0002467670, Pkib-202, Q04758]

101 query items

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