searching ... STRING: functional protein association networks

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The following proteins in Mus musculus appear to match your input.
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101 query items

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1) '10090.ENSMUSP00000105094':

Top1 - DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus remo [...] [a.k.a. ENSMUST00000129289, Topoisomerase (DNA) I, 21969]

2) '10090.ENSMUSP00000098366':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

3) '10090.ENSMUSP00000029382':

Ppid - Peptidyl-prolyl cis-trans isomerase D; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor co [...] [a.k.a. Peptidyl-prolyl isomerase D, ENSMUST00000159505.2, BC011499]

4) '10090.ENSMUSP00000031663':

C8b - Complement component C8 beta chain; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Belongs to the complement C6/C7/C8/C9 family. [a.k.a. UPI00000EB97B, CCDS84762.1, 4930439B20Rik]

5) '10090.ENSMUSP00000047334':

Wdr60 - WD repeat-containing protein 60; May play a role in ciliogenesis. [a.k.a. Wdr60-207, ENSMUST00000222764.1, ENSMUST00000221748.1]

6) '10090.ENSMUSP00000063461':

Slc35c1 - GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily. [a.k.a. MGI:2443301, FUCT1, Q8BLX4]

7) '10090.ENSMUSP00000051092':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

8) '10090.ENSMUSP00000033056':

Pycard - Apoptosis-associated speck-like protein containing a CARD; Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8- dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase- 9, -2 and -3. Involved in macrophage pyroptosis, a cas [...] [a.k.a. Q9D2W9, ENSMUSP00000033056, PYD and CARD domain-containing protein]

9) '10090.ENSMUSP00000032774':

Ttc23 - Tetratricopeptide repeat protein 23; Participates positively in the ciliary Hedgehog (Hh) signaling. [a.k.a. CCDS52270.1, XM_006541109, ENSMUSP00000103095]

10) '10090.ENSMUSP00000126448':

Acot1 - Acyl-coenzyme A thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating intracellular levels of acyl-CoAs, free fatty acids and CoASH. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20); Belongs to the C/M/P thioester hydrolase family. [a.k.a. NP_036136.1, ACOT1_MOUSE, ENSMUST00000222591]

11) '10090.ENSMUSP00000036472':

Rnf167 - E3 ubiquitin-protein ligase RNF167; May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin- conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition. [a.k.a. ENSMUST00000141237.1, ENSMUSP00000036472, XR_001780049.1]

12) '10090.ENSMUSP00000131943':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

13) '10090.ENSMUSP00000135827':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

14) '10090.ENSMUSP00000095929':

Mc1r - Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. [a.k.a. BC119294, NP_032585, CH466525]

15) '10090.ENSMUSP00000099744':

Tom1l2 - TOM1-like protein 2; Probable role in protein transport. May regulate growth factor-induced mitogenic signaling (By similarity); Belongs to the TOM1 family. [a.k.a. ENSMUSP00000099744, XP_017169940.1, ENSMUST00000093045]

16) '10090.ENSMUSP00000020846':

Srebf1 - Processed sterol regulatory element-binding protein 1; Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1- containing promoters. [a.k.a. NM_001313979.1, ENSMUST00000156304, CCDS24785.1]

17) '10090.ENSMUSP00000127715':

Tns1 - Tensin 1. [a.k.a. XM_017319853, XM_006495882.3, XM_006495878]

18) '10090.ENSMUSP00000005950':

Mmp12 - Macrophage metalloelastase; May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity). Belongs to the peptidase M10A family. [a.k.a. BAE42486.1, ENSMUST00000120655.7, M10.009]

19) '10090.ENSMUSP00000029400':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

20) '10090.ENSMUSP00000083761':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

101 query items

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