searching ... STRING: functional protein association networks

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The following proteins in Mus musculus appear to match your input.
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103 query items

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1) '10090.ENSMUSP00000138836':

Il6st - Interleukin-6 receptor subunit beta; Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases. That causes phosphorylation of IL6ST tyrosine residues which in turn activates STAT3. Mediates signals which regulate immune response, hematopoiesis, pain control and bone metabolism. Has a role in embryonic development. Does not bind IL6 (By similarity). Essential for [...] [a.k.a. ENSMUSP00000139311, Il6st-208, CD130]

2) '10090.ENSMUSP00000109151':

Tmem63b - CSC1-like protein 2; Acts as an osmosensitive calcium-permeable cation channel. Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion. Belongs to the CSC1 (TC 1.A.17) family. [a.k.a. D3YY83, XP_006524202, Tmem63b-206]

3) '10090.ENSMUSP00000030299':

Cyp2j5 - Cytochrome P450 2J5. [a.k.a. O54749, XM_006502720, Cytochrome P450 2J5]

4) '10090.ENSMUSP00000111081':

Steap4 - Metalloreductase STEAP4; Integral membrane protein that functions as NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (By similarity). Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance (By similarity). Involved in inflammatory arthri [...] [a.k.a. ENSMUSP00000111081, 117167, AK040760]

5) '10090.ENSMUSP00000049104':

Gbp7 - Guanylate-binding protein 7. [a.k.a. AC102108, DAA05846.1, ENSMUST00000171263]

6) '10090.ENSMUSP00000047771':

Atf5 - Cyclic AMP-dependent transcription factor ATF-5; Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'- C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcriptional activity is enhanced by CCND3 and s [...] [a.k.a. ENSMUSP00000103525, mmu:107503, NRIF3-associated protein]

7) '10090.ENSMUSP00000037371':

Echdc3 - Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. [a.k.a. Echdc3-201, uc008igi.1, NM_024208]

8) '10090.ENSMUSP00000019997':

Tnfaip3 - Tumor necrosis factor alpha-induced protein 3; Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in [...] [a.k.a. 5DQ6, XM_006512702, TNF alpha-induced protein 3]

9) '10090.ENSMUSP00000110209':

Tmprss7 - Transmembrane protease serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position; Belongs to the peptidase S1 family. [a.k.a. XM_006521915.2, XP_006521979.1, AK045663]

10) '10090.ENSMUSP00000009344':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

11) '10090.ENSMUSP00000103824':

Ccl1 - C-C motif chemokine 1; Cytokine that is chemotactic for neutrophils; Belongs to the intercrine beta (chemokine CC) family. [a.k.a. Ccl1-203, Scya1, ENSMUST00000138333.1]

12) '10090.ENSMUSP00000062607':

Pla2g4f - Cytosolic phospholipase A2 zeta; Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine than phosphatidylcholine. [a.k.a. UPI000050BCC9, NM_001363075.1, ENSMUST00000142183]

13) '10090.ENSMUSP00000029936':

Gbp2b - Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus (By similarity). Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. [a.k.a. mmu:14468, AC102108, Guanylate binding protein 2b]

14) '10090.ENSMUSP00000042905':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

15) '10090.ENSMUSP00000110102':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

16) '10090.ENSMUSP00000087394':

Slc44a5 - Choline transporter-like protein 5. [a.k.a. XP_006501558, MGI:3035141, XR_375526.3]

17) '10090.ENSMUSP00000130685':

Rnf43 - E3 ubiquitin-protein ligase RNF43; E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity). [a.k.a. Rnf43-207, AAH29717.1, Q6DI76]

18) '10090.ENSMUSP00000031235':

Gbp8 - Guanylate-binding protein 8. [a.k.a. Q2V6D6, ENSMUSP00000072663, ENSMUST00000072396]

19) '10090.ENSMUSP00000049404':

Znfx1 - NFX1-type zinc finger-containing protein 1. [a.k.a. MGI:2138982, 98999, BAE29390.1]

20) '10090.ENSMUSP00000034611':

Phldb1 - Pleckstrin homology-like domain family B member 1. [a.k.a. ENSMUSP00000034611, ENSMUSG00000048537, XM_017313085.1]

103 query items

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