searching ... STRING: functional protein association networks

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The following proteins in Rattus norvegicus appear to match your input.
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76 query items

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1) '10116.ENSRNOP00000001162':

Cd40lg - CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] [a.k.a. sCD40L, Tnfsf5, ENSRNOT00000001162]

2) '10116.ENSRNOP00000017227':

- - Sorry, STRING found no proteins by this name in Rattus norvegicus - -

3) '10116.ENSRNOP00000018742':

Pef1 - Peflin; Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. Together with PDCD6, acts as calcium-dependent adapter for the BCR(KLHL12) complex, a complex involved in endoplasmic reticulum (ER)-Golgi transport by regulating the size of COPII coats. In response to cytosolic calcium increase, the heterodimer formed with PDCD6 interacts with, and bridges together the BCR(KLHL12) complex and SEC31 (SEC31A or SEC31B), promoting monoubiquitination of SEC31 and subsequent collagen export, which is [...] [a.k.a. MGC95159, 297900, Q641Z8]

4) '10116.ENSRNOP00000001373':

- - Sorry, STRING found no proteins by this name in Rattus norvegicus - -

5) '10116.ENSRNOP00000007654':

Map3k7 - Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] [a.k.a. R-RNO-1280218, R-RNO-168164, R-RNO-450321]

6) '10116.ENSRNOP00000029963':

- - Sorry, STRING found no proteins by this name in Rattus norvegicus - -

7) '10116.ENSRNOP00000035782':

Lyrm1 - LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes. [a.k.a. NM_001276487, G3V950, NP_001263416.1]

8) '10116.ENSRNOP00000005996':

Pes1 - Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. [a.k.a. Q3B8N8, Pescadillo ribosomal biogenesis factor 1, R-RNO-6791226]

9) '10116.ENSRNOP00000067744':

Usp19 - Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing thier ubiq [...] [a.k.a. NM_001001516.2, XP_006243861.1, Ubiquitin carboxyl-terminal hydrolase 19]

10) '10116.ENSRNOP00000052492':

Tasp1 - Taspase, threonine aspartase 1 (Predicted). [a.k.a. XM_008762262, NP_001037708, ENSRNOT00000006024]

11) '10116.ENSRNOP00000028677':

Prune1 - Exopolyphosphatase PRUNE1; Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis. Involved in the regulation of microtubule polymerization; Belongs to the PPase class C family. Prune subfamily. [a.k.a. ENSRNOT00000028677, rno:310664, NM_001007697.1]

12) '10116.ENSRNOP00000043456':

- - Sorry, STRING found no proteins by this name in Rattus norvegicus - -

13) '10116.ENSRNOP00000009744':

- - Sorry, STRING found no proteins by this name in Rattus norvegicus - -

14) '10116.ENSRNOP00000045180':

- - Sorry, STRING found no proteins by this name in Rattus norvegicus - -

15) '10116.ENSRNOP00000033253':

Gart - Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. [a.k.a. Phosphoribosylformylglycinamidine cyclo-ligase, Glycinamide ribonucleotide synthetase, R-RNO-8956320]

16) '10116.ENSRNOP00000053740':

- - Sorry, STRING found no proteins by this name in Rattus norvegicus - -

17) '10116.ENSRNOP00000066618':

Lonp1 - Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] [a.k.a. Prss15, AB064323, NM_133404]

18) '10116.ENSRNOP00000026696':

Hspa9 - Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. [a.k.a. Peptide-binding protein 74, R-RNO-8953897, R-RNO-3371453]

19) '10116.ENSRNOP00000017019':

Irx2 - Iroquois homeobox 2. [a.k.a. NM_001039505, D3ZGA0_RAT, UPI000050803C]

20) '10116.ENSRNOP00000024796':

- - Sorry, STRING found no proteins by this name in Rattus norvegicus - -

76 query items

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