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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000220562':
EXTL3 - Exostosin-like 3; Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation.
[a.k.a. EC 2.4.1.224, HGNC:3518, exostosin like glycosyltransferase 3]
2) '9606.ENSP00000294409':
GMEB1 - Glucocorticoid modulatory element-binding protein 1; Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
[a.k.a. NP_001306603, XM_011540521.2, ENST00000456852]
3) '9606.ENSP00000379696':
PKIA - cAMP-dependent protein kinase inhibitor alpha; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
[a.k.a. 4WB7, 1XH5, 3OOG]
4) '9606.ENSP00000317971':
WDTC1 - WD and tetratricopeptide repeats protein 1; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
[a.k.a. R-HSA-8951664, Q9NV87, DCAF9]
5) '9606.ENSP00000296220':
OSBPL11 - Oxysterol-binding protein-related protein 11; Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage. Weakly binds 25- hydroxycholesterol ; Belongs to the OSBP family.
[a.k.a. 114885, XR_001739992, OSBP12]
6) '9606.ENSP00000300146':
PATL1 - Protein PAT1 homolog 1; RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV). Belongs to the PAT1 family.
[a.k.a. AL831992, Pat1b, OMIM:614660]
7) '9606.ENSP00000445704':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000221452':
RELB - Transcription factor RelB; NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishab [...]
[a.k.a. RELB-207, 5971, NP_006500.2]
9) '9606.ENSP00000294016':
ADCY9 - Adenylate cyclase type 9; Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors. Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors.
[a.k.a. I3L342, AC9, R-HSA-388396]
10) '9606.ENSP00000432456':
GPR61 - G-protein coupled receptor 61; Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. May be involved in the regulation of food intake and body weight (By similarity).
[a.k.a. ENSP00000432456, NM_031936.5, HGNC:13300]
11) '9606.ENSP00000446278':
LRTM2 - Leucine rich repeats and transmembrane domains 2.
[a.k.a. LRTM2-202, ENSG00000166159, ENSP00000446278]
12) '9606.ENSP00000376808':
CUL5 - Cullin-5; Core component of multiple SCF-like ECS (Elongin-Cullin 2/5- SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulate [...]
[a.k.a. R-HSA-8951664, XP_016873854, ENSP00000299351]
13) '9606.ENSP00000383599':
WDR47 - WD repeat domain 47.
[a.k.a. UPI0001F782CA, Neuronal enriched MAP-interacting protein, XM_017000697.1]
14) '9606.ENSP00000253048':
ZC3H4 - Zinc finger CCCH-type containing 4.
[a.k.a. NM_015168.2, NM_015168.1, XM_011526670]
15) '9606.ENSP00000256689':
SLC38A2 - Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.
[a.k.a. R-HSA-352230, 54407, ENST00000551374]
16) '9606.ENSP00000404991':
TMEM120B - Transmembrane protein 120B; Necessary for efficient adipogenesis. Belongs to the TMEM120 family.
[a.k.a. ENST00000342607.10, XM_017018853.1, HGNC:32008]
17) '9606.ENSP00000393667':
FAM126B - Protein FAM126B; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. Belongs to the FAM126 family.
[a.k.a. ENST00000418596.7, NM_001321622.1, XP_011509304]
18) '9606.ENSP00000410603':
FAM131B - Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family.
[a.k.a. ENST00000443739.6, NM_001371248.1, Q7L0D6]
19) '9606.ENSP00000402515':
SMG1 - Serine/threonine-protein kinase SMG1; Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense- mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1. Recruited by release factors to stalled ribosomes together with SMG8 and SMG9 (forming the SMG1C protein kinase complex), and UPF1 to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. In EJC-dependent NMD, the SURF complex associates with the exon junction compl [...]
[a.k.a. ENST00000565324, 23049, ENST00000568038.1]
20) '9606.ENSP00000296490':
WDR82 - WD repeat-containing protein 82; Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
[a.k.a. WDR82-202, SWD2, TMEM113]
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