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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000228434':
CD69 - Early activation antigen CD69; Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
[a.k.a. AIM, AAO63584.1, Z30427]
2) '9606.ENSP00000376505':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
3) '9606.ENSP00000269391':
RNF157 - E3 ubiquitin ligase RNF157; E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons. Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical. May act as a scaffold molecule to regulate this process. Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle.
[a.k.a. HGNC:29402, ENSP00000497353, ENST00000591355]
4) '9606.ENSP00000361345':
FAM78A - Protein FAM78A; Family with sequence similarity 78 member A; Belongs to the FAM78 family.
[a.k.a. ENST00000372269, XM_011518567, CCDS6941]
5) '9606.ENSP00000331614':
IKZF1 - DNA-binding protein Ikaros; Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus i [...]
[a.k.a. AC124014, CCDS59055.1, ENSP00000342378]
6) '9606.ENSP00000347088':
LARGE1 - LARGE xylosyl- and glucuronyltransferase 1; Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate- 6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongat [...]
[a.k.a. ENSP00000336636, CAI18788.1, BC117425]
7) '9606.ENSP00000358784':
KCNA3 - Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
[a.k.a. hsa:3738, uc001dzv.3, NP_002223]
8) '9606.ENSP00000259254':
GYPC - Glycophorin-C; This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
[a.k.a. HPA008965, XM_006712460, R-HSA-202733]
9) '9606.ENSP00000354498':
PHLDB1 - Pleckstrin homology like domain family B member 1.
[a.k.a. BAC76044.1, NX_Q86UU1, XM_011542713.2]
10) '9606.ENSP00000425487':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
11) '9606.ENSP00000434241':
KCNC3 - Potassium voltage-gated channel subfamily C member 3; Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. The channel displays rapid activation and inactivation kinetics. It plays a role in the regulation of the frequency, shape and duration of action potentials in Purkinje cells. Required for normal survival of cerebellar [...]
[a.k.a. ENSP00000303282, KSHIIID, NM_001372305.1]
12) '9606.ENSP00000348708':
UPF2 - Regulator of nonsense transcripts 2; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.
[a.k.a. ENSP00000346833, EAW86332.1, ENSP00000313356]
13) '9606.ENSP00000361800':
WDR34 - WD repeat-containing protein 34; Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL- 1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation.
[a.k.a. A2A3F8, XP_011517481, HPA040764]
14) '9606.ENSP00000296859':
RAPGEF6 - Rap guanine nucleotide exchange factor 6; Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.
[a.k.a. Rap guanine nucleotide exchange factor 6, RA-GEF-2, A3KN82]
15) '9606.ENSP00000363574':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
16) '9606.ENSP00000363640':
PHF1 - PHD finger protein 1; Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Involved in DNA damage response and is recruited at double-strand breaks (DSBs). Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex: it is however unclear whether recruitment of the PRC2 complex to H3K36me3 leads to enhance or inhibit H3K27me3 methylation mediated by the PRC2 complex. According to some reports, PRC2 recruitment by PHF1 promotes H3K27me3 and subsequent gene silencing by inducing [...]
[a.k.a. AL050332, URS00009C0556, ENSG00000112511]
17) '9606.ENSP00000371535':
SEPSECS - O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family.
[a.k.a. O-phosphoseryl-tRNA(Sec) selenium transferase, UPI0001D3B1F7, CAB62209.1]
18) '9606.ENSP00000478516':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
19) '9606.ENSP00000385739':
CEACAM21 - CEA cell adhesion molecule 21; Belongs to the immunoglobulin superfamily. CEA family.
[a.k.a. ENST00000482870.6, XM_005278397.4, XM_024451767.1]
20) '9606.ENSP00000380559':
CRAMP1 - Protein cramped-like; Cramped chromatin regulator homolog 1.
[a.k.a. ENSP00000399172, CRAMP1L, ENST00000492778.5]
101 query items
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