searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000240874':

KALRN - Kalirin; Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. [a.k.a. NR_028136.3, NP_001309922, R-HSA-388396]

2) '9606.ENSP00000468837':

M0QX08_HUMAN - Protein kinase domain-containing protein. [a.k.a. M0R0L4, ENST00000597712, ENST00000596586]

3) '9606.ENSP00000270223':

DMWD - Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing. [a.k.a. L19267, Q09019, ENSP00000270223]

4) '9606.ENSP00000345826':

PMEPA1 - Protein TMEPAI; Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may [...] [a.k.a. R-HSA-170834, PMEPA1-203, Q5JY37]

5) '9606.ENSP00000341208':

STAT5A - Signal transducer and activator of transcription 5A; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL- induced transcription. Regulates the expression of milk proteins during lactation. [a.k.a. STAT5, R-HSA-1226099, R-HSA-162582]

6) '9606.ENSP00000303211':

ACHE - Acetylcholinesterase; Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. Belongs to the type-B carboxylesterase/lipase family. [a.k.a. 6CQV, AAK21003.1, UPI0003F48229]

7) '9606.ENSP00000262659':

CCM2L - Cerebral cavernous malformations 2 protein-like; CCM2 like scaffold protein. [a.k.a. NX_Q9NUG4, CCM2L_HUMAN, XM_006723706.3]

8) '9606.ENSP00000263174':

PALMD - Palmdelphin. [a.k.a. CCDS758.1, palmdelphin, PALML]

9) '9606.ENSP00000440982':

RASA4B - RAS p21 protein activator 4B. [a.k.a. Ras GTPase-activating protein 4, ENSP00000303968, ENST00000495352.5]

10) '9606.ENSP00000361120':

RALGDS - Ral guanine nucleotide dissociation stimulator; Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap. [a.k.a. AB037729, ENSP00000305359, HGNC:9842]

11) '9606.ENSP00000361959':

CCN5 - CCN family member 5; May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production; Belongs to the CCN family. [a.k.a. CT58, NX_O76076, NP_003872.1]

12) '9606.ENSP00000436785':

SLC35F2 - Solute carrier family 35 member F2; Putative solute transporter. [a.k.a. UPI0001F77E13, NP_059985.2, 54733]

13) '9606.ENSP00000376703':

ANO4 - Anoctamin-4; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity). [a.k.a. ANO4-207, BAC03688.1, XM_017018812.2]

14) '9606.ENSP00000410852':

TMEM132C - Transmembrane protein 132C. [a.k.a. XR_001748922.1, Q8N3T6, NP_001129575]

15) '9606.ENSP00000463287':

KLF14 - Kruppel like factor 14. [a.k.a. BTEB5, Kruppel like factor 14, ENSP00000463287]

16) '9606.ENSP00000371341':

TNK2 - Activated CDC42 kinase 1; Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting [...] [a.k.a. 3EQP, 1U46, hsa:10188]

17) '9606.ENSP00000300305':

RUNX1 - Runt-related transcription factor 1; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T [...] [a.k.a. R-HSA-8939247, ENST00000479325, X90976]

18) '9606.ENSP00000319756':

TNS2 - Tensin-2; Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin. In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy. Negatively regulates PI3K-AKT pathway activation. [a.k.a. ENSP00000319684, ENST00000549498, C1-TEN]

19) '9606.ENSP00000346508':

PDGFA - Platelet-derived growth factor subunit A; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by t [...] [a.k.a. AAB26566.1, R-HSA-9006925, M20489]

20) '9606.ENSP00000349076':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

101 query items

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