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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000247153':
CFP - Properdin; A positive regulator of the alternate pathway (AP) of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).
[a.k.a. ENSP00000366204, XP_016885064.1, 5199]
2) '9606.ENSP00000483624':
CLECL1 - C-type lectin-like domain family 1; May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response.
[a.k.a. CLECL1-204, CCDS8603.1, NM_001267701]
3) '9606.ENSP00000365261':
LST1 - Leukocyte-specific transcript 1 protein; Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
[a.k.a. ENSP00000365260, HGNC:14189, ENST00000396112.6]
4) '9606.ENSP00000274306':
GZMA - Granzyme A; Abundant protease in the cytosolic granules of cytotoxic T- cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA. Belongs to the peptidase S1 family. Granzym [...]
[a.k.a. Granzyme A, NM_006144, OTTHUMG00000097011]
5) '9606.ENSP00000361803':
SMAP2 - Stromal membrane-associated protein 2; GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).
[a.k.a. NM_022733.3, stromal membrane-associated protein 1-like, ENSG00000084070]
6) '9606.ENSP00000246186':
MMP24 - Processed matrix metalloproteinase-24; Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to m [...]
[a.k.a. HGNC:7172, XP_016883087.1, 10893]
7) '9606.ENSP00000389414':
TBXAS1 - Thromboxane A synthase 1; Belongs to the cytochrome P450 family.
[a.k.a. NP_001353467.1, AAH14117.1, UPI000007035B]
8) '9606.ENSP00000322276':
VNN2 - Vascular non-inflammatory molecule 2; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil; Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
[a.k.a. ENST00000530536, BAF84814.1, R-HSA-196854]
9) '9606.ENSP00000429150':
FAM49B - Protein FAM49B.
[a.k.a. XM_011517114.2, NP_001340217.1, AAH17297.1]
10) '9606.ENSP00000365411':
APBB1IP - Amyloid beta A4 precursor protein-binding family B member 1-interacting protein; Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion; Belongs to the MRL family.
[a.k.a. R-HSA-162582, AAH35636.1, PREL1]
11) '9606.ENSP00000171757':
P2RY10 - Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins.
[a.k.a. R-HSA-388396, ENSG00000078589, BC095498]
12) '9606.ENSP00000378485':
MATK - Megakaryocyte-associated tyrosine-protein kinase; Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC- family members in brain by specifically phosphorylating their C- terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T- cell proliferation.
[a.k.a. ENSP00000378481, ENST00000310132.10, ENST00000591059.1]
13) '9606.ENSP00000356033':
TAGAP - T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation.
[a.k.a. ENSP00000356028, ENSP00000356033, R-HSA-162582]
14) '9606.ENSP00000249071':
RAC2 - Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
[a.k.a. RAC2-201, NM_002872.5, R-HSA-9006925]
15) '9606.ENSP00000293373':
NCKAP1L - Nck-associated protein 1-like; Essential hematopoietic-specific regulator of the actin cytoskeleton (Probable). Controls lymphocyte development, activation, proliferation and homeostasis, erythrocyte membrane stability, as well as phagocytosis and migration by neutrophils and macrophages. Component of the WAVE2 complex which signals downstream of RAC to stimulate F-actin polymerization. Required for stabilization and/or translation of the WAVE2 complex proteins in hematopoietic cells (By similarity). Exhibits complex cycles of activation and inhibition to generate waves of propagating [...]
[a.k.a. AAA35964.1, NP_001171905.1, NCKAP1L-204]
16) '9606.ENSP00000284154':
GRAP - GRB2-related adapter protein; Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. Plays a role in the inner ear and in hearing.
[a.k.a. R-HSA-162582, GRB2 related adaptor protein, NM_006613.4]
17) '9606.ENSP00000472929':
VAV1 - Proto-oncogene vav; Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
[a.k.a. AF030223, R-HSA-388396, VAV1-206]
18) '9606.ENSP00000379980':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
19) '9606.ENSP00000294507':
LAPTM5 - Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells; Belongs to the LAPTM4/LAPTM5 transporter family.
[a.k.a. NX_Q13571, KIAA0085, AAA74018.1]
20) '9606.ENSP00000337393':
UXT - Protein UXT; Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription. Together with URI1, associates with chromatin to the NKX3-1 promoter region. Negatively regulates the transcriptional activity of the estrogen receptor ESR1 by inducing its translocation into the cytoplasm. May act as nuclear chaperone that facilitates the formation of the NF-kappa-B enhanceosome and thus positively regulates NF-kappa-B transcription activity. Potential component of mitochondrial-associated LRPPRC, a multidomain orga [...]
[a.k.a. B2R561, 8409, Q9Y6E5]
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