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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000256951':
EMP1 - Epithelial membrane protein 1.
[a.k.a. ENST00000256951, epithelial membrane protein 1, O00681]
2) '9606.ENSP00000419153':
ZBTB20 - Zinc finger and BTB domain-containing protein 20; May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).
[a.k.a. ENSP00000349803, ZBTB20-220, NP_001335729]
3) '9606.ENSP00000358404':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000370340':
NFIB - Nuclear factor 1 B-type; Transcriptional activator of GFAP, essential for proper brain development. Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family.
[a.k.a. A0A1B0GVN4, AL137017, NP_001356391]
5) '9606.ENSP00000424827':
NEDD4 - E3 ubiquitin-protein ligase NEDD4; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Specifically ubiquitinates 'Lys-63' in target proteins. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. [...]
[a.k.a. NP_001271268, R-HSA-9006925, R-HSA-8948747]
6) '9606.ENSP00000386200':
FOXP2 - Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
[a.k.a. ENSP00000377133, ABG77460.1, HPA001679]
7) '9606.ENSP00000351022':
TPM1 - Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
[a.k.a. UPI00022F85DA, HPA047089, CAA30930.1]
8) '9606.ENSP00000425556':
PALLD - Palladin; Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have [...]
[a.k.a. NP_001354498.1, ENSP00000422135, XP_011530073]
9) '9606.ENSP00000376297':
DYNLL1 - Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1; Belongs to the dynein light c [...]
[a.k.a. R-HSA-2555396, dynein light chain LC8-type 1, R-HSA-69278]
10) '9606.ENSP00000304408':
COL3A1 - Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
[a.k.a. R-HSA-6806834, H7C435, R-HSA-8948216]
11) '9606.ENSP00000427211':
APBB2 - Amyloid-beta A4 precursor protein-binding family B member 2; May modulate the internalization of amyloid-beta precursor protein.
[a.k.a. ENST00000513611, XM_017008151.2, XP_016863641]
12) '9606.ENSP00000287916':
CLDN12 - Claudin-12; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
[a.k.a. LOC102723899, CCDS5618.1, NP_001172002.1]
13) '9606.ENSP00000302913':
SH3D19 - SH3 domain-containing protein 19; May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.
[a.k.a. XP_016863267, AAH85613.2, Q9UFC8]
14) '9606.ENSP00000264634':
WNT5A - Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decre [...]
[a.k.a. XM_011534089.1, WNT-5A protein, WNT5A-203]
15) '9606.ENSP00000405890':
PBX1 - Pre-B-cell leukemia transcription factor 1; Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhanc [...]
[a.k.a. PBX homeobox 1, R-HSA-5619507, ENSP00000405890]
16) '9606.ENSP00000361151':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
17) '9606.ENSP00000276925':
CDKN2B - Cyclin-dependent kinase 4 inhibitor B; Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest; Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
[a.k.a. R-HSA-170834, R-HSA-69278, ENST00000579591.1]
18) '9606.ENSP00000353377':
CCDC102B - Coiled-coil domain containing 102B.
[a.k.a. XM_017025976.1, XR_935251.2, ENSG00000150636]
19) '9606.ENSP00000342626':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
20) '9606.ENSP00000352208':
MYOF - Myoferlin; Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity).
[a.k.a. AAF27177.1, AAH40110.1, Myoferlin]
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