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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000257789':
ORC3 - Origin recognition complex subunit 3; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3; Belongs to the ORC3 family.
[a.k.a. NX_Q9UBD5, ENST00000257789, R-HSA-69278]
2) '9606.ENSP00000385790':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
3) '9606.ENSP00000330658':
PAPPA - Pappalysin-1; Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. Belongs to the peptidase M43B family.
[a.k.a. uc004bjn.4, 3.4.24.79, DIPLA1]
4) '9606.ENSP00000359782':
BEND6 - BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis.
[a.k.a. XP_016865896.1, C6orf65, BEND6_HUMAN]
5) '9606.ENSP00000348753':
SPRED2 - Sprouty-related, EVH1 domain-containing protein 2; Negatively regulates Ras signaling pathways and downstream activation of MAP kinases.
[a.k.a. Q2NKX6, R-HSA-190236, 2JP2]
6) '9606.ENSP00000370936':
E2F6 - Transcription factor E2F6; Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'- TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overex [...]
[a.k.a. NM_198256.3, R-HSA-69278, ENST00000421117.1]
7) '9606.ENSP00000266458':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000314036':
AGPAT4 - 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).
[a.k.a. XM_006715514.3, ENST00000437165.1, R-HSA-556833]
9) '9606.ENSP00000368752':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000339381':
RGS12 - Regulator of G-protein signaling 12; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form.
[a.k.a. RGS12-219, R-HSA-388396, R-HSA-162582]
11) '9606.ENSP00000378845':
LAT - Linker for activation of T-cells family member 1; Required for TCR (T-cell antigen receptor)- and pre-TCR- mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeleta [...]
[a.k.a. ENST00000395456.6, B7WPI0, NP_001014988.1]
12) '9606.ENSP00000312143':
TNS3 - Tensin-3; May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development (By similarity); Belongs to the PTEN phosphatase protein family.
[a.k.a. Tensin 3, AK092864, Q68CZ2]
13) '9606.ENSP00000363667':
PTPN3 - Tyrosine-protein phosphatase non-receptor type 3; May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.
[a.k.a. ENSP00000378304, 5774, XP_016870444.1]
14) '9606.ENSP00000394757':
ZNF516 - Zinc finger protein 516; Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity). May also play a role in the cellular response to replication stress.
[a.k.a. NP_055458, OTTHUMG00000165995, XM_017026097]
15) '9606.ENSP00000261712':
PSMD11 - 26S proteasome non-ATPase regulatory subunit 11; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. P [...]
[a.k.a. Proteasome 26S subunit, non-ATPase 11, R-HSA-2555396, R-HSA-174084]
16) '9606.ENSP00000345405':
SPRED3 - Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase.
[a.k.a. OTTHUMG00000182082, NP_001035987, K7EPU5]
17) '9606.ENSP00000296098':
TRIM54 - Tripartite motif-containing protein 54; May bind and stabilize microtubules during myotubes formation.
[a.k.a. uc002rjn.4, ENST00000380073, ENST00000349868]
18) '9606.ENSP00000412363':
ZNF438 - Zinc finger protein 438; Isoform 1 acts as a transcriptional repressor.
[a.k.a. Q5T427, ENSP00000364460, XM_011519373.3]
19) '9606.ENSP00000386959':
CAPS2 - Calcyphosin-2; Calcyphosine 2.
[a.k.a. ENST00000322382, CCDS73497, NP_115995]
20) '9606.ENSP00000357052':
DCAF8 - DDB1- and CUL4-associated factor 8; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
[a.k.a. ENSP00000318227, R-HSA-8951664, ENSP00000413688]
101 query items
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