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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000261254':
CCND2 - G1/S-specific cyclin-D2; Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...]
[a.k.a. ENST00000536537, AAA51926.1, R-HSA-69278]
2) '9606.ENSP00000432869':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
3) '9606.ENSP00000225777':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000462099':
RASSF5 - Ras association domain-containing protein 5; Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras [...]
[a.k.a. AAH04270.1, Ras association domain-containing protein 5, Ras association domain family member 5]
5) '9606.ENSP00000366271':
KDM2B - Lysine-specific demethylase 2B; Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin liga [...]
[a.k.a. F5H4X4, XM_011538867.3, ENSP00000366271]
6) '9606.ENSP00000267205':
RHOF - Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology.
[a.k.a. R-HSA-162582, ENST00000541657.5, ENST00000537265.5]
7) '9606.ENSP00000364265':
FOXE1 - Forkhead box protein E1; Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.
[a.k.a. O00358, 2304, ENSP00000364262]
8) '9606.ENSP00000357575':
CFAP46 - Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement.
[a.k.a. ENST00000305220, C10orf93, ENSP00000357575]
9) '9606.ENSP00000386884':
CXCR4 - C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade. Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Involved in hematopoiesis and in car [...]
[a.k.a. R-HSA-162587, R-HSA-388396, CD184]
10) '9606.ENSP00000377771':
SIPA1 - Signal-induced proliferation-associated protein 1; GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state. Affects cell cycle progression (By similarity).
[a.k.a. ENST00000530226.1, SPA1, XM_005274189.2]
11) '9606.ENSP00000331614':
IKZF1 - DNA-binding protein Ikaros; Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus i [...]
[a.k.a. AC124014, CCDS59055.1, ENSP00000342378]
12) '9606.ENSP00000340975':
SOWAHD - Ankyrin repeat domain-containing protein SOWAHD; Sosondowah ankyrin repeat domain family member D; Belongs to the SOWAH family.
[a.k.a. UPI0000197588, A6NJG2, Sosondowah ankyrin repeat domain family member D]
13) '9606.ENSP00000344562':
CORO6 - Coronin-6; Coronin 6.
[a.k.a. hsa:84940, J3QLV6, ENST00000459686]
14) '9606.ENSP00000221922':
CCDC9 - Coiled-coil domain containing 9.
[a.k.a. coiled-coil domain containing 9, CCDS12698.1, Coiled-coil domain-containing protein 9]
15) '9606.ENSP00000334872':
MT1F - Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.
[a.k.a. ENST00000567672, AAA59588.1, 4494]
16) '9606.ENSP00000477059':
XKR7 - XK-related protein 7; XK related 7.
[a.k.a. 343702, hsa:343702, AAT07094.1]
17) '9606.ENSP00000226067':
HLF - Hepatic leukemia factor; HLF transcription factor, PAR bZIP family member; Belongs to the bZIP family. PAR subfamily.
[a.k.a. Q6FHS9, NM_002126, BAG37547.1]
18) '9606.ENSP00000301039':
PROCA1 - Protein interacting with cyclin A1; Belongs to the PROCA1 family.
[a.k.a. HGNC:28600, PROCA1-208, CCDS11239.1]
19) '9606.ENSP00000482620':
RAB11FIP4 - Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.
[a.k.a. NP_001333678.1, uc032fao.2, NP_001333676.1]
20) '9606.ENSP00000385746':
SMS - Spermine synthase; Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).
[a.k.a. ENSP00000368740, BC009898, ENST00000362081]
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