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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000261623':
CYBA - Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. Belongs to the p22phox family.
[a.k.a. XM_011522905.3, R-HSA-1222556, R-HSA-162582]
2) '9606.ENSP00000339328':
PLAUR - Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
[a.k.a. UPAR, CCDS74386.1, ENSP00000339328]
3) '9606.ENSP00000369456':
ITPA - Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
[a.k.a. NM_181493, AF219116, AAK21848.1]
4) '9606.ENSP00000464443':
IFT20 - Intraflagellar transport protein 20 homolog; Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling. Essential for male fertility. Plays an important role in spermatogenesis, particularly sperm [...]
[a.k.a. ENSP00000484842, Intraflagellar transport 20, J3KRU2]
5) '9606.ENSP00000466134':
PRKCSH - Glucosidase 2 subunit beta; Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity).
[a.k.a. PRKCSH-202, ENSP00000465821, NM_001289102.1]
6) '9606.ENSP00000368952':
STOML3 - Stomatin-like protein 3; Required for the function of many mechanoreceptors. Modulate mechanotransduction channels and acid-sensing ion channels (ASIC) proteins. Potentiates PIEZO1 and PIEZO2 function by increasing their sensitivity to mechanical stimulations; Belongs to the band 7/mec-2 family.
[a.k.a. STOML3-201, UPI000003615B, SRO]
7) '9606.ENSP00000367911':
SYCE1L - Synaptonemal complex central element protein 1-like; May be involved in meiosis.
[a.k.a. MRP2, NM_001129979.3, meiosis-related protein]
8) '9606.ENSP00000271628':
SF3B4 - Splicing factor 3B subunit 4; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare clas [...]
[a.k.a. NX_Q15427, HPA028578, 6AH0]
9) '9606.ENSP00000436152':
TP53I11 - Tumor protein p53 inducible protein 11.
[a.k.a. ENSP00000433474, XP_016874069.1, E9PIN5]
10) '9606.ENSP00000243346':
NMI - N-myc-interactor; May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5; Belongs to the NMI family.
[a.k.a. NP_004679, ENST00000491771.5, AAH21987.1]
11) '9606.ENSP00000374234':
TMEM72 - Transmembrane protein 72.
[a.k.a. ENST00000544540, 643236, uc001jbn.3]
12) '9606.ENSP00000383715':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
13) '9606.ENSP00000298048':
MELK - Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1. Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis. Plays a key role in cell proliferation and carcino [...]
[a.k.a. 4D2P, NM_014791.3, XP_011516381.1]
14) '9606.ENSP00000411198':
KRTAP4-16 - Keratin associated protein 4-16.
[a.k.a. KRTAP4-16P, ENSG00000241241, 85354]
15) '9606.ENSP00000361405':
MMP9 - 67 kDa matrix metalloproteinase-9; May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Belongs to the peptidase M10A family.
[a.k.a. AAA51539.1, Matrix metallopeptidase 9, 4WZV]
16) '9606.ENSP00000251496':
NCAPG - Condensin complex subunit 3; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
[a.k.a. XM_017008543.2, CND3_HUMAN, R-HSA-69278]
17) '9606.ENSP00000263867':
CAPG - Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
[a.k.a. ENSP00000386596, ENSP00000398232, NP_001307662.1]
18) '9606.ENSP00000249504':
HOXD11 - Homeobox protein Hox-D11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.
[a.k.a. NM_021192.2, P31277, Homeobox protein Hox-4F]
19) '9606.ENSP00000336831':
PLS1 - Plastin-1; Actin-bundling protein in the absence of calcium.
[a.k.a. XP_016862115, XP_011511202.1, ENST00000483507.1]
20) '9606.ENSP00000353646':
PLEKHG4 - Puratrophin-1; Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi.
[a.k.a. NP_001123200, ENST00000569875.5, HPA055696]
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