searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000261693':

SCARB1 - Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Belongs to the CD36 family. [a.k.a. Q52LZ5, UPI000189A7D4, NP_001076428.1]

2) '9606.ENSP00000264896':

SCARB2 - Lysosome membrane protein 2; Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. [a.k.a. 4TVZ, ENST00000452464, Lysosome membrane protein 2]

3) '9606.ENSP00000358571':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000428056':

PIK3R1 - Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] [a.k.a. R-HSA-388396, R-HSA-912526, R-HSA-1643713]

5) '9606.ENSP00000333024':

PHF7 - PHD finger protein 7; May play a role in spermatogenesis. [a.k.a. PHF7-203, HSPC226, PHF7-208]

6) '9606.ENSP00000405424':

OXR1 - Oxidation resistance protein 1; May be involved in protection from oxidative damage. [a.k.a. ENST00000517455.1, ENSP00000379172, BAC04711.1]

7) '9606.ENSP00000352673':

ELF3 - ETS-related transcription factor Elf-3; Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effec [...] [a.k.a. NP_004424.3, R-HSA-162582, CAG33387.1]

8) '9606.ENSP00000446121':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000371331':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000443598':

FAM214A - Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. [a.k.a. FAM214A-205, ENST00000570204.1, XP_005254604]

11) '9606.ENSP00000357283':

LMNA - Prelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. A [...] [a.k.a. R-HSA-2555396, NP_733821.1, ENST00000504687]

12) '9606.ENSP00000478637':

SYT16 - Synaptotagmin-16; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent. [a.k.a. ENST00000568344.5, XP_024305492.1, OMIM:610950]

13) '9606.ENSP00000265085':

CPEB4 - Cytoplasmic polyadenylation element-binding protein 4; Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism. Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE- regulated mRNAs in conditions in which global protein synthesis is inhibited (By similarity). Required for [...] [a.k.a. ENSP00000334533, CCDS4390.1, ENST00000334035.9]

14) '9606.ENSP00000339086':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000382767':

SEL1L3 - Protein sel-1 homolog 3; SEL1L family member 3. [a.k.a. ENSP00000264868, SE1L3_HUMAN, KIAA0746]

16) '9606.ENSP00000262113':

MYOM2 - Myomesin-2; Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent. [a.k.a. CAA48832.1, P54296, AAH52969.1]

17) '9606.ENSP00000309772':

CPED1 - Cadherin like and PC-esterase domain containing 1. [a.k.a. ENST00000310396, ENST00000450913.6, NM_024913]

18) '9606.ENSP00000259365':

TMOD1 - Tropomodulin-1; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. [a.k.a. uc004axk.3, NM_001166116, HPA051202]

19) '9606.ENSP00000401437':

LDB3 - LIM domain-binding protein 3; May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. [a.k.a. NM_001080116.1, Q5K6P1, NM_001080115.2]

20) '9606.ENSP00000262844':

AMMECR1 - AMMECR nuclear protein 1. [a.k.a. HGNC:467, 9949, Q5JYV9]

101 query items

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