searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000262113':

MYOM2 - Myomesin-2; Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent. [a.k.a. CAA48832.1, P54296, AAH52969.1]

2) '9606.ENSP00000363993':

PSMB9 - Proteasome subunit beta type-9; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. [a.k.a. ENST00000395330, R-HSA-2555396, CAB015180]

3) '9606.ENSP00000362401':

CYSLTR1 - Cysteinyl leukotriene receptor 1; Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. [a.k.a. R-HSA-388396, NM_006639.3, ENST00000373304]

4) '9606.ENSP00000258499':

USP44 - Ubiquitin carboxyl-terminal hydrolase 44; Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts [...] [a.k.a. XP_011537107, OTTHUMG00000170281, Ubiquitin thioesterase 44]

5) '9606.ENSP00000468271':

K7ERI5_HUMAN - KRAB domain-containing protein. [a.k.a. ENSG00000267173, uc060zrn.1, ENST00000588212]

6) '9606.ENSP00000306070':

NUDT6 - Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation. Belongs to the Nudix hydrolase family. [a.k.a. ENST00000502270.5, NUDT6-205, gfg]

7) '9606.ENSP00000468862':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000247829':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000377549':

FABP6 - Gastrotropin; Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). ECO:0000250|UniProtKB:P51162, ; Belongs to the calycin superfamily. Fatty-acid binding prot [...] [a.k.a. I-BAP, H0YB64, ENST00000393980]

10) '9606.ENSP00000341442':

SNTN - Sentan; May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules. [a.k.a. ENST00000469440, SNTN-202, S100AL]

11) '9606.ENSP00000301488':

CDK2AP2 - Cyclin-dependent kinase 2-associated protein 2; Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes (By similarity). Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A. [a.k.a. CDK2AP2-203, Q6IAV4, CDKA2_HUMAN]

12) '9606.ENSP00000384000':

ZNF681 - Zinc finger protein 681; May be involved in transcriptional regulation. [a.k.a. E9PSC0, B3KVF7, FLJ31526]

13) '9606.ENSP00000377854':

LHX6 - LIM/homeobox protein Lhx6; Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex (By similarity). [a.k.a. ENST00000558672, CCDS6837, NM_199160]

14) '9606.ENSP00000241261':

TNFSF10 - Tumor necrosis factor ligand superfamily member 10; Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. Belongs to the tumor necrosis factor family. [a.k.a. U37518, ENST00000494851, AAV38371.1]

15) '9606.ENSP00000436042':

PCDHA9 - Protocadherin alpha-9; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. [a.k.a. PCDH-ALPHA9, Q9Y5H5, PCDHA9-202]

16) '9606.ENSP00000260382':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000295117':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000353971':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

19) '9606.ENSP00000369654':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000417291':

REPIN1 - Replication initiator 1; Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'- ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending. [a.k.a. XP_024302506.1, NP_055189.2, XP_024302505.1]

101 query items

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