searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000269187':

SLC39A6 - Zinc transporter ZIP6; May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. [a.k.a. BAG61161.1, ZIP6, solute carrier family 39 member 6]

2) '9606.ENSP00000256343':

CATSPERB - Cation channel sperm-associated protein subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. [a.k.a. URS00008B280C, ENST00000556429, AAI26215.1]

3) '9606.ENSP00000484415':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000453793':

MEIS2 - Homeobox protein Meis2; Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element; MEIS2 is not involved in complex DNA-binding. Probably in [...] [a.k.a. ENSP00000323442, UPI000002ADE2, ENSP00000380745]

5) '9606.ENSP00000447378':

MGAM - Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. [a.k.a. NM_001365693, XM_011516672.2, E9PEQ5]

6) '9606.ENSP00000385727':

MAST4 - Microtubule associated serine/threonine kinase family member 4; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. [a.k.a. XP_011541686.1, ENST00000403625, ENSP00000384313]

7) '9606.ENSP00000378400':

LIMA1 - LIM domain and actin-binding protein 1; Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments. Plays a role in cholesterol homeostasis. Influences plasma cholesterol levels through regulation of intestinal cholesterol absorption. May act as a scaffold protein by regulating NPC1L1 transportation, an essential protein for cholesterol absorption, [...] [a.k.a. NM_016357, AF157325, Q9HBN5]

8) '9606.ENSP00000223862':

RLN1 - Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. [a.k.a. NM_006911, AF104934, BC005956]

9) '9606.ENSP00000420939':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000457466':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000265362':

SEMA3A - Semaphorin-3A; Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1; Belongs to the semaphorin family. [a.k.a. XP_011514036.1, ENST00000424555, XM_006715839.3]

12) '9606.ENSP00000377494':

TAGLN3 - Transgelin-3; Transgelin 3. [a.k.a. NM_013259, ENSP00000377494, NP_037391]

13) '9606.ENSP00000438040':

CCDC91 - Coiled-coil domain-containing protein 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes. [a.k.a. hsa:55297, ENST00000543019.1, ENST00000539107]

14) '9606.ENSP00000439807':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000327821':

XPOT - Exportin-T; Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to tRNA and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the tRNA from the export receptor. XPOT then return to the nuclear compartment and mediate another round of transport. The directionality of nucl [...] [a.k.a. ENST00000389162, XPO3, Exportin-T]

16) '9606.ENSP00000379287':

YWHAZ - 14-3-3 protein zeta/delta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation. In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity). Belongs to the 14-3-3 family. [a.k.a. ENST00000353245.7, 4ZDR, ENST00000395951.7]

17) '9606.ENSP00000362244':

MAP7D1 - MAP7 domain containing 1; Belongs to the MAP7 family. [a.k.a. ENSP00000362243, CAB66482.2, ENST00000527764]

18) '9606.ENSP00000295934':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

19) '9606.ENSP00000287008':

PCDH1 - Protocadherin-1; May be involved in cell-cell interaction processes and in cell adhesion. [a.k.a. HGNC:8655, ENST00000287008, ENST00000503492]

20) '9606.ENSP00000364190':

PBX2 - Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1. [a.k.a. NM_002586.5, URS0000D6E18C, PBX2-205]

101 query items

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