searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000274024':

FABP2 - Fatty acid-binding protein, intestinal; FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. [a.k.a. R-HSA-556833, CAB047325, NP_000125]

2) '9606.ENSP00000333196':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000386138':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000370129':

AKR1C2 - Aldo-keto reductase family 1 member C2; Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5- beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha- androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. [a.k.a. P52895, ENSP00000397161, uc057rik.1]

5) '9606.ENSP00000372023':

CHEK2 - Serine/threonine-protein kinase Chk2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Regulates cell cycle checkpoint arrest through phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads [...] [a.k.a. 4A9S, 2XBJ, R-HSA-5693565]

6) '9606.ENSP00000246117':

NCLN - Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family. [a.k.a. Q969V3, K7ELZ9, UPI0000227DB8]

7) '9606.ENSP00000308279':

C9orf131 - Uncharacterized protein C9orf131; Chromosome 9 open reading frame 131. [a.k.a. AL353795, AL133575, ENST00000421362]

8) '9606.ENSP00000259881':

PSORS1C1 - Psoriasis susceptibility 1 candidate 1. [a.k.a. BC104870, AF484418, B0V083]

9) '9606.ENSP00000440626':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000431840':

SLC24A4 - Sodium/potassium/calcium exchanger 4; Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis (By similarity). Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. [a.k.a. XP_011534744.1, ENST00000532405, Solute carrier family 24 member 4]

11) '9606.ENSP00000368813':

KLHL34 - Kelch-like protein 34; Kelch like family member 34. [a.k.a. BC109031, ENSP00000368813, Kelch-like protein 34]

12) '9606.ENSP00000301280':

CHAF1A - Chromatin assembly factor 1 subunit A; Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly [...] [a.k.a. ENSG00000167670, CAF-1, ENST00000589648.1]

13) '9606.ENSP00000381628':

PCDHA12 - Protocadherin alpha-12; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. [a.k.a. Q2M1N8, NP_061726, NM_031864.2]

14) '9606.ENSP00000216923':

ZFP64 - Zinc finger protein 64; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. [a.k.a. ENST00000477786.5, ENSG00000020256, BAB14182.1]

15) '9606.ENSP00000387075':

TRABD2A - Metalloprotease TIKI1; Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. [a.k.a. LOC105374836, ENST00000460991, ENST00000474298.5]

16) '9606.ENSP00000391490':

AGR2 - Anterior gradient protein 2 homolog; Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion. [a.k.a. AAF22484.1, B5MC07, ENST00000468419]

17) '9606.ENSP00000338345':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000399979':

SLC52A1 - Solute carrier family 52, riboflavin transporter, member 1; Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption. [a.k.a. R-HSA-196854, PAR2, ENSP00000399979]

19) '9606.ENSP00000344446':

FGD6 - FYVE, RhoGEF and PH domain-containing protein 6; May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity). [a.k.a. 55785, Q9P2I5, ENST00000451107]

20) '9606.ENSP00000410007':

FBXO46 - F-box only protein 46; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. [a.k.a. NP_001073938, F-box protein 46, NP_001316561]

101 query items

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