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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000278919':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
2) '9606.ENSP00000221403':
DHDH - Dihydrodiol dehydrogenase; Belongs to the Gfo/Idh/MocA family.
[a.k.a. hsa:27294, ENST00000520557.1, EC 1.1.1.179]
3) '9606.ENSP00000377823':
NDRG4 - Protein NDRG4; Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
[a.k.a. ENSP00000454274, ENST00000565430, EAW82979.1]
4) '9606.ENSP00000242208':
INHBA - Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins; Belongs to the TGF-beta family.
[a.k.a. X04447, R-HSA-1502540, 1S4Y]
5) '9606.ENSP00000260653':
SIX3 - Homeobox protein SIX3; Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon. Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression. In addition, Six3 activity is re [...]
[a.k.a. AF092047, ENST00000260653.4, OTTHUMG00000152424]
6) '9606.ENSP00000342278':
OAS2 - 2'-5'-oligoadenylate synthase 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. Activated by detection of double stranded RNA (dsRNA): polymerizes higher oligomers of 2'-5'- oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNASEL) leading to its dimerization and subsequent activation. Activation of RNASEL leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antivi [...]
[a.k.a. 2-5A synthase 2, A8K9T1, XR_001748725.2]
7) '9606.ENSP00000261211':
CDK17 - Cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity). Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
[a.k.a. XM_017019406.1, XM_017019405.1, ENST00000550971]
8) '9606.ENSP00000294338':
PDZK1IP1 - PDZK1-interacting protein 1; May play an important role in tumor biology.
[a.k.a. PDZ1I_HUMAN, CCDS546, 17 kDa membrane-associated protein]
9) '9606.ENSP00000468500':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000384620':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
11) '9606.ENSP00000255631':
HSPBP1 - Hsp70-binding protein 1; Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
[a.k.a. ENSP00000465690, Hsp70-interacting protein 2, NP_001284529.1]
12) '9606.ENSP00000270586':
PSMB6 - Proteasome subunit beta type-6; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...]
[a.k.a. R-HSA-2555396, A0A087X2I4, R-HSA-174084]
13) '9606.ENSP00000284486':
FAM167A - Protein FAM167A; Family with sequence similarity 167 member A; Belongs to the FAM167 (SEC) family.
[a.k.a. XM_011543840.3, ENSP00000381384, XM_005272398.5]
14) '9606.ENSP00000324105':
ENO3 - Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.
[a.k.a. ENO3-201, NP_001180432.1, B4DUI6]
15) '9606.ENSP00000454229':
CLN3 - Battenin; Involved in microtubule-dependent, anterograde transport of late endosomes and lysosomes.
[a.k.a. CCDS73854, ENSP00000454466, H3BQ48]
16) '9606.ENSP00000297988':
AQP7 - Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity). Belongs to the MIP/aqua [...]
[a.k.a. LOC112267859, AQP7-207, ENSP00000485081]
17) '9606.ENSP00000346697':
BMF - Bcl-2-modifying factor; May play a role in apoptosis. Isoform 1 seems to be the main initiator.
[a.k.a. R-HSA-139910, NM_001003940.2, ENST00000561282]
18) '9606.ENSP00000317891':
TNIP1 - TNFAIP3-interacting protein 1; Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B- dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1- dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this f [...]
[a.k.a. ENSP00000430279, KIAA0113, Q15025]
19) '9606.ENSP00000295822':
EIF5A2 - Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By s [...]
[a.k.a. ENSG00000163577, UPI0000035FC3, NM_020390.5]
20) '9606.ENSP00000362507':
CCDC167 - Coiled-coil domain containing 167.
[a.k.a. CC167_HUMAN, AL353597, 154467]
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