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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000279263':
TM7SF2 - Delta(14)-sterol reductase TM7SF2; Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis.
[a.k.a. ENST00000534371.5, ENSP00000431685, ENST00000532328.5]
2) '9606.ENSP00000298681':
SLC39A2 - Zinc transporter ZIP2; Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis.
[a.k.a. R-HSA-425410, 6A1, NM_001256588]
3) '9606.ENSP00000369695':
MLLT3 - Protein AF-9; Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Recognizes and binds histone H3 crotonylated at 'Lys-9' (H3K9cr), and with slightly lower affinity histone H3 crotonylate [...]
[a.k.a. 2LM0, 5YYF, ENST00000380321]
4) '9606.ENSP00000469205':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000380779':
TCTN1 - Tectonic-1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to rep [...]
[a.k.a. AAQ88551.1, ENSP00000448664, Q49A60]
6) '9606.ENSP00000378427':
C5orf24 - UPF0461 protein C5orf24; Chromosome 5 open reading frame 24; Belongs to the UPF0461 family.
[a.k.a. NM_152409, ENST00000507390, ENST00000316107]
7) '9606.ENSP00000333779':
EVI2B - Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells.
[a.k.a. ENSG00000185862, AC134669, AAA35816.1]
8) '9606.ENSP00000242351':
ZC3HAV1 - Zinc finger CCCH-type antiviral protein 1; Antiviral protein which inhibits the replication of viruses by recruiting the cellular RNA degradation machineries to degrade the viral mRNAs. Binds to a ZAP-responsive element (ZRE) present in the target viral mRNA, recruits cellular poly(A)-specific ribonuclease PARN to remove the poly(A) tail, and the 3'-5' exoribonuclease complex exosome to degrade the RNA body from the 3'-end. It also recruits the decapping complex DCP1-DCP2 through RNA helicase p72 (DDX17) to remove the cap structure of the viral mRNA to initiate its degradation from the [...]
[a.k.a. ENSP00000349539, ENSP00000420107, ENSG00000105939]
9) '9606.ENSP00000373301':
SH3BP5 - SH3 domain-binding protein 5; Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25. Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B- cells. May be involved in BCR-induced apoptotic cell death.
[a.k.a. ENSP00000388553, UPI000198C947, CCDS43055.1]
10) '9606.ENSP00000289707':
SLAMF8 - SLAM family member 8; May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
[a.k.a. SLAM family member 8, XM_011509777.3, 56833]
11) '9606.ENSP00000222390':
HGF - Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
[a.k.a. NP_000592, ENST00000644543, HGF-202]
12) '9606.ENSP00000270792':
SH3BGRL3 - SH3 domain-binding glutamic acid-rich-like protein 3; Could act as a modulator of glutaredoxin biological activity.
[a.k.a. ENST00000614679, ENSG00000142669, BC030135]
13) '9606.ENSP00000322192':
PGA3 - Pepsin A-3; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
[a.k.a. pepsinogen A3, P00790, EC 3.4.23.1]
14) '9606.ENSP00000313600':
ATP10B - Probable phospholipid-transporting ATPase VB; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable); Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
[a.k.a. AC008456, AB018258, NM_001366655.1]
15) '9606.ENSP00000264711':
DNAJC27 - DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
[a.k.a. NP_001185488, NP_057628, RabJS]
16) '9606.ENSP00000387784':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
17) '9606.ENSP00000367817':
PODXL - Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...]
[a.k.a. NP_005388.2, O00592, ENSP00000440518]
18) '9606.ENSP00000302719':
KCNAB3 - Voltage-gated potassium channel subunit beta-3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5.
[a.k.a. KCNAB3-202, ENSP00000461290, XM_017025306.1]
19) '9606.ENSP00000176763':
STK10 - Serine/threonine-protein kinase 10; Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.
[a.k.a. O94804, NP_005981.3, ENST00000519441]
20) '9606.ENSP00000380349':
CAPN3 - Calpain-3; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family.
[a.k.a. H3BMH1, BC100782, UPI0000E59BEA]
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