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The following proteins in
Homo sapiens
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99 query items
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1) '9606.ENSP00000288937':
MRPL17 - Mitochondrial ribosomal protein L17.
[a.k.a. CCDS31412.1, R-HSA-5368286, 5OOM]
2) '9606.ENSP00000223073':
RBM28 - RNA-binding protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes.
[a.k.a. ENST00000495327.1, UPI0001B79306, XM_017012389]
3) '9606.ENSP00000427772':
WWC1 - Protein KIBRA; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migrati [...]
[a.k.a. hsa:23286, PPP1R168, ENSG00000113645]
4) '9606.ENSP00000373272':
TRIM71 - E3 ubiquitin-protein ligase TRIM71; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance (Probable). Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A (By similarity). In addition, participates in post-transcriptional mRNA repression in a miRNA independent mechanism. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and preven [...]
[a.k.a. NM_001039111.2, tripartite motif containing 71, DQ232881]
5) '9606.ENSP00000355249':
E2F2 - Transcription factor E2F2; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner; Belongs to the E2F/DP family.
[a.k.a. Transcription factor E2F2, R-HSA-69278, E2F transcription factor 2]
6) '9606.ENSP00000260983':
HECW2 - E3 ubiquitin-protein ligase HECW2; E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition.
[a.k.a. E3 ubiquitin-protein ligase HECW2, 57520, XM_024453021]
7) '9606.ENSP00000376141':
MFSD6 - Major facilitator superfamily domain containing 6; Belongs to the major facilitator superfamily. MFSD6 family.
[a.k.a. UPI000188185D, Q6ZSS7, HGNC:24711]
8) '9606.ENSP00000253462':
GINS2 - DNA replication complex GINS protein PSF2; The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
[a.k.a. R-HSA-69278, Pfs2, ENST00000595355]
9) '9606.ENSP00000256319':
ERG28 - Ergosterol biosynthesis 28 homolog; Belongs to the ERG28 family.
[a.k.a. AF136971, Q9UKR5, 11161]
10) '9606.ENSP00000263726':
LHX4 - LIM/homeobox protein Lhx4; May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. Binds preferentially to methylated DNA.
[a.k.a. XM_011510108.2, Q8WWX2, LHX4-201]
11) '9606.ENSP00000254605':
RRP8 - Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...]
[a.k.a. UPI00001580F8, nucleomethylin, 2ZFU]
12) '9606.ENSP00000343690':
DPYSL3 - Dihydropyrimidinase-related protein 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
[a.k.a. OTTHUMG00000163437, CAA69153.1, R-HSA-399956]
13) '9606.ENSP00000268989':
SGSM2 - Small G protein signaling modulator 2; Possesses GTPase activator activity towards RAB32, RAB33B and RAB38. Regulates the trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes by inactivating RAB32 and RAB38. Inhibits RAB32 and RAB38 activation both directly by promoting their GTPase activity and indirectly by disrupting the RAB9A-HPS4 interaction which is required for RAB32/38 activation. Belongs to the RUTBC family.
[a.k.a. NM_001098509.1, SGSM2-208, NP_001091979]
14) '9606.ENSP00000298159':
CFL2 - Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity); Belongs to the actin-binding proteins ADF family.
[a.k.a. AAH22364.1, LRG_213t1, NP_068733]
15) '9606.ENSP00000280527':
CRIM1 - Processed cysteine-rich motor neuron 1 protein; May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.
[a.k.a. ENSP00000415706, ENST00000477491.5, XP_011531201.1]
16) '9606.ENSP00000363157':
TNFSF15 - Tumor necrosis factor ligand superfamily member 15, membrane form; Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. Belongs to the tumor necrosis factor family.
[a.k.a. A0A0U5JA19, TL1, LN874313]
17) '9606.ENSP00000311713':
OXSR1 - Serine/threonine-protein kinase OSR1; Phosphorylates RELL1, RELL2 and RELT. Phosphorylates PAK1. Phosphorylates PLSCR1 in the presence of RELT. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
[a.k.a. BAA75674.1, OTTHUMG00000131084, XR_001740397.1]
18) '9606.ENSP00000476792':
RTL5 - Retrotransposon Gag like 5.
[a.k.a. Q8NCM4, Q5HYW3, RGAG4]
19) '9606.ENSP00000222753':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
20) '9606.ENSP00000434614':
CDC27 - Cell division cycle protein 27 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Belongs to the APC3/CDC27 family.
[a.k.a. ENST00000570818.5, R-HSA-2555396, R-HSA-174084]
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