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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000296484':
POC1A - POC1 centriolar protein homolog A; Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation; Belongs to the WD repeat POC1 family.
[a.k.a. XR_001740088, CCDS54592.1, NM_001161580.2]
2) '9606.ENSP00000328236':
KNTC1 - Kinetochore-associated protein 1; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
[a.k.a. XM_017020256.2, R-HSA-2555396, ENST00000535410.1]
3) '9606.ENSP00000321656':
CDC25C - M-phase inducer phosphatase 3; Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
[a.k.a. UPI0001D3B7C0, ENST00000297180, XP_011542062]
4) '9606.ENSP00000340279':
SSX2IP - Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin- catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha- actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via [...]
[a.k.a. XM_024453018, ENST00000481102.5, S4R403]
5) '9606.ENSP00000242776':
DDX39A - ATP-dependent RNA helicase DDX39A; [Isoform 1]: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus; Belongs to the DEAD box helicase family. DECD subfamily.
[a.k.a. ENST00000587730, XM_024451310.1, ENST00000591275]
6) '9606.ENSP00000400433':
HNRNPF - Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
[a.k.a. NP_001091678.1, P52597, NM_001098204]
7) '9606.ENSP00000272091':
SDE2 - Replication stress response regulator SDE2; Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP- box. The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis. The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain. The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner. Binding of SDE2 to PCNA is necessary to counteract dam [...]
[a.k.a. NP_689821, hsa:163859, ENSP00000355782]
8) '9606.ENSP00000476499':
ZBTB8B - Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.
[a.k.a. BAC03863.1, NP_001139192.1, AK092326]
9) '9606.ENSP00000334675':
ERCC6L - DNA excision repair protein ERCC-6-like; DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. Functions as ATP-dependent DNA translocase. Can promote Holliday junction branch migration (in vitro).
[a.k.a. Q9NXQ8, R-HSA-2555396, R-HSA-69278]
10) '9606.ENSP00000234488':
CLCN6 - Chloride transport protein 6; Chloride transport protein, initially identified as voltage- gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter; Belongs to the chloride channel (TC 2.A.49) family. ClC- 6/CLCN6 subfamily.
[a.k.a. CLCN6-204, NM_001286.3, ENSP00000423407]
11) '9606.ENSP00000354213':
HS3ST3B1 - Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to antico [...]
[a.k.a. BAG51220.1, CH471108, NP_006032]
12) '9606.ENSP00000435634':
C1orf94 - Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.
[a.k.a. AAH64845.1, E9PJ76, NM_001134734]
13) '9606.ENSP00000317177':
PLD6 - Mitochondrial cardiolipin hydrolase; Endonuclease that plays a critical role in PIWI-interacting RNA (piRNA) biogenesis during spermatogenesis. piRNAs provide essential protection against the activity of mobile genetic elements (By similarity). piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation (By similarity). Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface (By similarity). Al [...]
[a.k.a. R-HSA-1483148, phospholipase D family, member 6, hsa:201164]
14) '9606.ENSP00000326371':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
15) '9606.ENSP00000261377':
REXO5 - RNA exonuclease 5.
[a.k.a. NP_001185982, AL162035, hsa:81691]
16) '9606.ENSP00000253024':
TRIM28 - Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]
[a.k.a. 10155, CHEMBL3769297, 6QAJ]
17) '9606.ENSP00000431254':
IGLL5 - Immunoglobulin lambda like polypeptide 5.
[a.k.a. 100423062, NP_001243225.1, ENSP00000480519]
18) '9606.ENSP00000259806':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
19) '9606.ENSP00000344741':
INSIG1 - Insulin-induced gene 1 protein; Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin- mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. May pla [...]
[a.k.a. A4D2N1, INSIG1-205, MGC1405]
20) '9606.ENSP00000335463':
KNL1 - Kinetochore scaffold 1; Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.
[a.k.a. Q8NG31, R-HSA-2555396, ENST00000531626]
101 query items
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