searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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99 query items

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1) '9606.ENSP00000296529':

TMEM144 - Transmembrane protein 144; Belongs to the TMEM144 family. [a.k.a. CCDS3799.1, ENSP00000420930, URS0000EB0A1F]

2) '9606.ENSP00000339145':

RRP1B - Ribosomal RNA processing protein 1 homolog B; Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1. Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus. Involved in regulation of mRNA splicing (By similarity). Inhibits SIPA1 GTPase activity (By similarity). Involved in regulating expression of extracellular matrix genes (By similarity). Associates with chromatin and may play a role in modulating chromatin structure. [a.k.a. NM_015056, CCDS33577, ENSG00000160208]

3) '9606.ENSP00000334657':

TRIM46 - Tripartite motif-containing protein 46; Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration; Belongs to the TRIM/RBCC family. [a.k.a. ENST00000368384, AC234582, CCDS72932.1]

4) '9606.ENSP00000415836':

ZNF276 - Zinc finger protein 276; May be involved in transcriptional regulation. [a.k.a. MGC45417, NP_001106997.1, UPI0002467268]

5) '9606.ENSP00000358460':

CLIC2 - Chloride intracellular channel protein 2; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx. [a.k.a. CH471172, CLIC2_HUMAN, O15247]

6) '9606.ENSP00000469445':

PNMA3 - Paraneoplastic antigen Ma3; PNMA family member 3; Belongs to the PNMA family. [a.k.a. NP_037496, ENSP00000469445, CH471172]

7) '9606.ENSP00000251453':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000344431':

DNAJB13 - DnaJ homolog subfamily B member 13; Plays a role in the formation of the central complex of ciliary and flagellar axonemes. [a.k.a. 374407, NX_P59910, Q8IZW5]

9) '9606.ENSP00000358884':

CYB561D1 - Cytochrome b561 family member D1. [a.k.a. FLJ44753, uc010ovn.3, NP_001127874.1]

10) '9606.ENSP00000357057':

CASQ1 - Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca(2+) entry (SOCE) activity. [a.k.a. NM_001231, uc010pja.3, Calsequestrin, skeletal muscle isoform]

11) '9606.ENSP00000262304':

PKD1 - Polycystin-1; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Both PKD1 and PKD2 are required for channel activity. Involved in renal tubulogenesis. Involved in fluid- flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling (By similarity). The cilium length resp [...] [a.k.a. ENST00000567355.1, XP_024306067, ENST00000471603]

12) '9606.ENSP00000300571':

GPRC5B - G-protein coupled receptor family C group 5 member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. [a.k.a. ENST00000569847, ENST00000300571, ENST00000570142]

13) '9606.ENSP00000312244':

MSL3 - Male-specific lethal 3 homolog; Has a role in chromatin remodeling and transcriptional regulation. Has a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex. [a.k.a. NP_523353, UPI000006E6B7, MSL3-238]

14) '9606.ENSP00000324287':

ACAP2 - Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). [a.k.a. ACAP2-208, ENST00000480906, ENST00000475905]

15) '9606.ENSP00000265421':

POLB - DNA polymerase beta; Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. [a.k.a. 4PHE, 4UAY, 1BPY]

16) '9606.ENSP00000329880':

PHACTR1 - Phosphatase and actin regulator 1; Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity. Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity). [a.k.a. CH471087, NP_001309238, ENSP00000368631]

17) '9606.ENSP00000433109':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000269298':

SAT2 - Diamine acetyltransferase 2; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine. [a.k.a. CCDS82055, hsa:112483, ENST00000571195]

19) '9606.ENSP00000345230':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000339681':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

99 query items

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