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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000306528':
DESI2 - Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization.
[a.k.a. ENSP00000306528, ENST00000391840, NP_001284675.1]
2) '9606.ENSP00000312734':
RAB8B - Ras-related protein Rab-8B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).
[a.k.a. Q92930, NP_057614.1, AAH20654.1]
3) '9606.ENSP00000360939':
CMPK1 - UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
[a.k.a. AL607122, ENST00000371873, 51727]
4) '9606.ENSP00000251496':
NCAPG - Condensin complex subunit 3; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
[a.k.a. XM_017008543.2, CND3_HUMAN, R-HSA-69278]
5) '9606.ENSP00000452181':
VIPAS39 - Spermatogenesis-defective protein 39 homolog; Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of VPS33B. May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indir [...]
[a.k.a. uc001xtu.3, NP_001180244.1, VIPAS39-205]
6) '9606.ENSP00000250495':
NEDD8 - NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
[a.k.a. R-HSA-170834, R-HSA-8951664, uc001wnn.3]
7) '9606.ENSP00000345008':
FBLN5 - Fibulin-5; Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. Belongs to the fibulin family.
[a.k.a. R-HSA-2129379, ENST00000557088.5, ENST00000554121]
8) '9606.ENSP00000338770':
ZNF420 - Zinc finger protein 420; May be involved in transcriptional regulation.
[a.k.a. ENST00000587029.5, ENST00000589245, NM_144689]
9) '9606.ENSP00000336866':
RBBP9 - Serine hydrolase RBBP9; Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1.
[a.k.a. NM_006606, ENST00000202818, XP_005260709.1]
10) '9606.ENSP00000403400':
CCPG1 - Cell cycle progression protein 1; Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation. Belongs to the CCPG1 family.
[a.k.a. ENST00000563171, ENST00000564663, CCDS55966.1]
11) '9606.ENSP00000382508':
CDIP1 - Cell death-inducing p53-target protein 1; Acts as an important p53/TP53-apoptotic effector. Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner. Belongs to the CDIP1/LITAF family.
[a.k.a. Q9H305, CDIP, ENSP00000454994]
12) '9606.ENSP00000375822':
ZNF222 - Zinc finger protein 222; May be involved in transcriptional regulation.
[a.k.a. XM_005259208, CCDS33045, XM_017027238]
13) '9606.ENSP00000281182':
ACAD8 - Isobutyryl-CoA dehydrogenase, mitochondrial; Isobutyryl-CoA dehydrogenase which catalyzes one of the steps of the valine catabolic pathway. To a lesser extent, is also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA.
[a.k.a. XM_017017546, ENST00000525961.1, XP_016873036.1]
14) '9606.ENSP00000420727':
ZNF181 - Zinc finger protein 181; May be involved in transcriptional regulation.
[a.k.a. XM_005258850.2, AAH43228.1, ENSP00000471063]
15) '9606.ENSP00000379143':
ZNF32 - Zinc finger protein 32; May be involved in transcriptional regulation.
[a.k.a. X52361, Zinc finger protein KOX30, AAB09561.1]
16) '9606.ENSP00000429986':
ENY2 - Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]
[a.k.a. Q9NPA8, 56943, AAF89829.1]
17) '9606.ENSP00000302843':
DNAJC18 - DnaJ heat shock protein family member C18.
[a.k.a. D6RB44, AC142391, ENST00000505268]
18) '9606.ENSP00000341657':
THYN1 - Thymocyte nuclear protein 1; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
[a.k.a. ENSP00000341657, NP_001032381, NP_954995.1]
19) '9606.ENSP00000376583':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
20) '9606.ENSP00000343515':
TCEA2 - Transcription elongation factor A protein 2; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Belongs to the TFS-II family.
[a.k.a. ENST00000477783, ENST00000477783.5, TCEA2_HUMAN]
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