searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Homo sapiens appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

101 query items

showing page 1 of 6 • first • previous • next • last

1) '9606.ENSP00000312134':

PRG2 - Eosinophil granule major basic protein; Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. [a.k.a. Q6ICT2, 5553, NP_001230174.1]

2) '9606.ENSP00000484689':

IFITM2 - Interferon-induced transmembrane protein 2; IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBO [...] [a.k.a. Interferon induced transmembrane protein 2, 10581, IFITM2-204]

3) '9606.ENSP00000312741':

CAMKK2 - Calcium/calmodulin-dependent protein kinase kinase 2; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals ( [...] [a.k.a. 6BQQ, R-HSA-388396, R-HSA-9619229]

4) '9606.ENSP00000466897':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000349588':

ANK2 - Ankyrin-2; Plays an essential role in the localization and membrane stabilization of ion transporters and ion channels in several cell types, including cardiomyocytes, as well as in striated muscle cells. In skeletal muscle, required for proper localization of DMD and DCTN4 and for the formation and/or stability of a special subset of microtubules associated with costameres and neuromuscular junctions. In cardiomyocytes, required for coordinate assembly of Na/Ca exchanger, SLC8A1/NCX1, Na/K ATPases ATP1A1 and ATP1A2 and inositol 1,4,5- trisphosphate (InsP3) receptors at sarcoplasmic re [...] [a.k.a. NM_001354257.1, XM_017008072.2, NP_001341175.1]

6) '9606.ENSP00000262768':

TIMP2 - Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. Belongs to the protease inhibitor I35 (TIMP) family. [a.k.a. 7077, CSC-21K, ENSP00000262768]

7) '9606.ENSP00000344855':

FBXL14 - F-box/LRR-repeat protein 14; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1. [a.k.a. HPA053889, NP_689654, R-HSA-8951664]

8) '9606.ENSP00000379396':

NAV2 - Neuron navigator 2; Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs; Belongs to the Nav/unc-53 family. [a.k.a. Neuron navigator 2, CAD32556.1, 2YRN]

9) '9606.ENSP00000378409':

VSIR - V-type immunoglobulin domain-containing suppressor of T-cell activation; Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14- mediated MMP2 activation. [a.k.a. A1L0X9, VSIR-203, ENST00000394957.7]

10) '9606.ENSP00000316649':

OSBPL2 - Oxysterol-binding protein-related protein 2; Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro). [a.k.a. Oxysterol binding protein like 2, ENST00000644535.1, ENSP00000495166]

11) '9606.ENSP00000480890':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000381857':

MROH6 - Maestro heat like repeat family member 6. [a.k.a. Maestro heat like repeat family member 6, XM_011517214.1, XP_006716678.1]

13) '9606.ENSP00000206423':

CCDC80 - Coiled-coil domain-containing protein 80; Promotes cell adhesion and matrix assembly. [a.k.a. AY333429, NP_955805, SSG1]

14) '9606.ENSP00000418397':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000454783':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000359378':

PRRG3 - Transmembrane gamma-carboxyglutamic acid protein 3; Proline rich and Gla domain 3. [a.k.a. BC128256, PRRG3-203, ENSP00000498287]

17) '9606.ENSP00000222990':

SNX8 - Sorting nexin-8; May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network. [a.k.a. C9IYC5, ENSP00000406954, CCDS5331]

18) '9606.ENSP00000485022':

U2AF1L5 - U2 small nuclear RNA auxiliary factor 1 like 5. [a.k.a. ENST00000620065, HPA052083, XM_017028220.1]

19) '9606.ENSP00000328335':

SMIM10 - Small integral membrane protein 10. [a.k.a. ENSP00000328335, chromosome X open reading frame 69, AAH08642.1]

20) '9606.ENSP00000248071':

KLF2 - Krueppel-like factor 2; Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription. Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements. Belongs to the krueppel C2H2-type zinc-finger protein family. [a.k.a. 10365, ABK41959.1, Kruppel-like factor 2 (lung)]

101 query items

showing page 1 of 6 • first • previous • next • last

<- Back ⤓ Mapping Continue ->

© STRING Consortium 2023

Credits

Access

Info

About