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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000314508':
GBA - Lysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...]
[a.k.a. NX_P04062, Imiglucerase, glucosylceramidase]
2) '9606.ENSP00000246117':
NCLN - Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family.
[a.k.a. Q969V3, K7ELZ9, UPI0000227DB8]
3) '9606.ENSP00000478570':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000343331':
LIPI - Lipase member I; Hydrolyzes specifically phosphatidic acid (PA) to produce 2- acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). Belongs to the AB hydrolase superfamily. Lipase family.
[a.k.a. Lipase member I, NM_001302998.2, OTTHUMG00000074258]
5) '9606.ENSP00000403067':
FRMD5 - FERM domain-containing protein 5; May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation.
[a.k.a. NM_001322949.2, CCDS10107, UPI0000EE4F9C]
6) '9606.ENSP00000440626':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000312134':
PRG2 - Eosinophil granule major basic protein; Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
[a.k.a. Q6ICT2, 5553, NP_001230174.1]
8) '9606.ENSP00000362201':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000262345':
IL12RB2 - Interleukin-12 receptor subunit beta-2; Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
[a.k.a. H0Y5V0, XP_006710680.1, Q99665]
10) '9606.ENSP00000301280':
CHAF1A - Chromatin assembly factor 1 subunit A; Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly [...]
[a.k.a. ENSG00000167670, CAF-1, ENST00000589648.1]
11) '9606.ENSP00000385142':
NRXN1 - Neurexin-1; Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N- terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect [...]
[a.k.a. CCDS82449.1, UPI0005C1219A, AC007680]
12) '9606.ENSP00000411152':
ITPKB - Inositol-trisphosphate 3-kinase B.
[a.k.a. inositol 1,4,5-trisphosphate 3-kinase B, ENST00000341334, Q5VWM0]
13) '9606.ENSP00000247191':
DLGAP5 - Disks large-associated protein 5; Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
[a.k.a. Disks large-associated protein 5, NM_001146015.1, R-HSA-162582]
14) '9606.ENSP00000311218':
C1orf100 - Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.
[a.k.a. OTTHUMG00000040104, XM_011544128, NM_001276349]
15) '9606.ENSP00000282561':
GJA1 - Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...]
[a.k.a. ENSG00000152661, CAA37122.1, AAD37802.2]
16) '9606.ENSP00000338345':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
17) '9606.ENSP00000375855':
PDC - Phosducin; May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX. Belongs to the phosducin family.
[a.k.a. ENST00000497198, MEKA, M38059]
18) '9606.ENSP00000245503':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
19) '9606.ENSP00000403644':
DDC - Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs to the group II decarboxylase family.
[a.k.a. NP_001229816.1, Aromatic-L-amino-acid decarboxylase, BC008366]
20) '9606.ENSP00000263805':
ZNF106 - Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.
[a.k.a. AL832014, Q86T50, AK302735]
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