searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Homo sapiens appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

101 query items

showing page 1 of 6 • first • previous • next • last

1) '9606.ENSP00000315017':

MRPL1 - Mitochondrial ribosomal protein L1. [a.k.a. XR_001741317.1, Q96BW3, R-HSA-5368286]

2) '9606.ENSP00000367697':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000274026':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000315988':

DPY19L2 - Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family. [a.k.a. XM_017019203, ENST00000439061, XP_024304712.1]

5) '9606.ENSP00000376946':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000339390':

CDH26 - Cadherin-like protein 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Ligand for integrins alpha-E/beta-7, ITGAE:ITGAB7, alpha-4/beta-7, ITGA4:ITGAB7 and alpha-4/beta-1, ITGA4:ITGAB1 through which modulates CD4(+) T cells activation. [a.k.a. XP_011527271.1, Q9NTY2, ENSP00000339390]

7) '9606.ENSP00000372023':

CHEK2 - Serine/threonine-protein kinase Chk2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Regulates cell cycle checkpoint arrest through phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads [...] [a.k.a. 4A9S, 2XBJ, R-HSA-5693565]

8) '9606.ENSP00000288266':

APPL1 - DCC-interacting protein 13-alpha; Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism. Regulates signaling pathway leading to cell proliferation through interaction with RAB5A and subunits of the NuRD/MeCP1 complex. Functions as a positive regulator of innate immune response via activation of AKT1 signaling pathway by forming a complex with APPL1 and PIK3R1 (By similarity). Inhibits Fc-gamma receptor-mediated pha [...] [a.k.a. 26060, 2Q12, AB037849]

9) '9606.ENSP00000438040':

CCDC91 - Coiled-coil domain-containing protein 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes. [a.k.a. p56, ENSP00000440513, ENST00000541792.1]

10) '9606.ENSP00000420270':

UHMK1 - Serine/threonine-protein kinase Kist; Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity). [a.k.a. ENST00000538489, Q8TAS1, ENST00000323192]

11) '9606.ENSP00000359693':

FKBP1C - FKBP prolyl isomerase 1C. [a.k.a. hCG_1998784, ENSP00000359693, CH471143]

12) '9606.ENSP00000327009':

CLIP4 - CAP-Gly domain containing linker protein family member 4. [a.k.a. HGNC:26108, XR_939718, XR_002959339]

13) '9606.ENSP00000444412':

ZNF268 - Zinc finger protein 268; [Isoform 1]: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression; Belongs to the krueppel C2H2-type zinc-finger protein family. [a.k.a. 2EMX, ENSP00000437858, ENST00000540096]

14) '9606.ENSP00000441927':

SESN3 - Sestrin-3; May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity). [a.k.a. BAH13685.1, SEST3, 143686]

15) '9606.ENSP00000263826':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000359216':

PTBP2 - Polypyrimidine tract-binding protein 2; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. [a.k.a. AL357150, Polypyrimidine tract-binding protein 2, NR_125357.2]

17) '9606.ENSP00000319918':

ITFG1 - T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family. [a.k.a. H3BUJ1, AC007494, Protein TIP]

18) '9606.ENSP00000360436':

ENPP5 - Ectonucleotide pyrophosphatase/phosphodiesterase family member 5; Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates. Lacks lysopholipase D activity. May play a role in neuronal cell communication; Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. [a.k.a. Q9UJA9, XP_005249317, ENSP00000360440]

19) '9606.ENSP00000264866':

TBC1D19 - TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). [a.k.a. ENST00000264866.8, ENST00000502873, 55296]

20) '9606.ENSP00000411532':

TOP2A - DNA topoisomerase 2-alpha; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity). [a.k.a. TOP2A-201, AF064590, NP_001058.2]

101 query items

showing page 1 of 6 • first • previous • next • last

<- Back ⤓ Mapping Continue ->

© STRING Consortium 2023

Credits

Access

Info

About