searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000315702':

MOB4 - MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. [a.k.a. CAG33652.1, AK292938, CGI-95]

2) '9606.ENSP00000262653':

CBFA2T2 - Protein CBFA2T2; Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Via association with PRDM14 is involved in regulation of embryonic stem cell (ESC) pluripotency. Involved in primordial germ cell (PCG) formation. Stabilizes PRDM14 and OCT4 on chromatin in a homooligomerization- dependent manner (By similarity). Can repress the expression of MMP7 in a ZBTB33-dependent manner. May function as a complex with the chimeric protein RUNX1/AML1 [...] [a.k.a. ENSP00000352622, ENST00000342704, XP_011527405.1]

3) '9606.ENSP00000387020':

ARHGEF33 - Rho guanine nucleotide exchange factor 33; May act as a guanine-nucleotide releasing factor. [a.k.a. R-HSA-388396, ARHGEF33-206, ARHGEF33-205]

4) '9606.ENSP00000255006':

RIN2 - Ras and Rab interactor 2; Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP. Belongs to the RIN (Ras interaction/interference) family. [a.k.a. Ras and Rab interactor 2, XP_005260790, XP_011527560.1]

5) '9606.ENSP00000327533':

LYG2 - Lysozyme g-like protein 2; May act as a potent antibacterial protein that may play a role in the innate immunity; Belongs to the glycosyl hydrolase 23 family. [a.k.a. XM_017003751, EAX01873.1, LYG2-201]

6) '9606.ENSP00000370770':

C17orf107 - Uncharacterized protein C17orf107; Chromosome 17 open reading frame 107. [a.k.a. CCDS45591.1, uc002fzl.4, AK128415]

7) '9606.ENSP00000384620':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000438689':

ACADVL - Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, myristoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons. Belongs to the acyl-CoA dehydrogenase family. [a.k.a. ENST00000578319, NM_001270447.1, ENST00000580263.5]

9) '9606.ENSP00000276585':

MRPS28 - Mitochondrial ribosomal protein S28; Belongs to the bacterial ribosomal protein bS1 family. [a.k.a. R-HSA-5368286, S35mt, ENST00000521434.5]

10) '9606.ENSP00000377036':

PTPA - Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine- protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the var [...] [a.k.a. 5524, ENST00000358994.8, ENST00000414510]

11) '9606.ENSP00000333275':

NR2C1 - Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiatio [...] [a.k.a. XR_944700, NR2C1-209, NP_001120834.1]

12) '9606.ENSP00000340445':

SAXO2 - Stabilizer of axonemal microtubules 2. [a.k.a. ENSG00000188659, NP_001335631.1, SAXO2-203]

13) '9606.ENSP00000426638':

ETFDH - Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone; Belongs to the ETF-QO/FixC family. [a.k.a. CCDS3800, CCDS64090.1, ENST00000510353]

14) '9606.ENSP00000341139':

C3orf62 - Uncharacterized protein C3orf62; Chromosome 3 open reading frame 62. [a.k.a. ENSP00000413663, ENST00000479673, NX_Q6ZUJ4]

15) '9606.ENSP00000274496':

YIPF5 - Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi. [a.k.a. CAH18295.1, BC007829, NP_001020118]

16) '9606.ENSP00000401721':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000308279':

C9orf131 - Uncharacterized protein C9orf131; Chromosome 9 open reading frame 131. [a.k.a. AL353795, AL133575, ENST00000421362]

18) '9606.ENSP00000361066':

NCOA3 - Nuclear receptor coactivator 3; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via [...] [a.k.a. Q9Y6Q9, AAC51663.1, R-HSA-5619507]

19) '9606.ENSP00000363794':

HSD17B8 - Estradiol 17-beta-dehydrogenase 8; NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heterotetramer with CBR4 has NADH- dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. Belongs to the short-chain dehydrogenases/reductases (SDR) family. [a.k.a. FABGL, RING2, R-HSA-556833]

20) '9606.ENSP00000365777':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

101 query items

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