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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000341170':
PTN - Pleiotrophin; Secreted growth factor that mediates its signal through cell- surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups. Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration in several tissues namely neuron and bone. Also plays a role in synaptic plasticity and learning-related behavior by inhibiting long-term synaptic potentiation (By similarity). Binds PTPRZ1, leading to neutralization of the negative charges of the CS ch [...]
[a.k.a. ENST00000393083, KF458612, OMIM:162095]
2) '9606.ENSP00000379696':
PKIA - cAMP-dependent protein kinase inhibitor alpha; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
[a.k.a. 4WB7, 1XH5, 3OOG]
3) '9606.ENSP00000360431':
PLCE1 - 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T- cell activation.
[a.k.a. NM_001288989, XP_006717948, ENST00000285974]
4) '9606.ENSP00000306253':
ITPR1 - Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
[a.k.a. A0A3B3ISR4, ITPR1-226, R-HSA-388396]
5) '9606.ENSP00000354878':
KIF21A - Kinesin-like protein KIF21A; Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-end directed motor activity (By similarity).
[a.k.a. Q7Z4S6, KIF21A-209, FEOM1]
6) '9606.ENSP00000410309':
PDE1A - Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
[a.k.a. UPI0000001072, R-HSA-388396, R-HSA-9006925]
7) '9606.ENSP00000340465':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000432614':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000479964':
SLC4A1AP - Kanadaptin; Solute carrier family 4 member 1 adaptor protein.
[a.k.a. HLC3, 4H87, AAH98302.1]
10) '9606.ENSP00000329904':
IQCF2 - IQ motif containing F2.
[a.k.a. ENSP00000329904, CCDS2835, ENSG00000184345]
11) '9606.ENSP00000264414':
CUL3 - Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cu [...]
[a.k.a. ENST00000409777, R-HSA-8951664, CUL3-206]
12) '9606.ENSP00000344489':
RNF133 - E3 ubiquitin-protein ligase RNF133; Has E3 ubiquitin-protein ligase activity.
[a.k.a. HGNC:21154, EAW83577.1, RING-type E3 ubiquitin transferase RNF133]
13) '9606.ENSP00000386213':
MYO3B - Myosin-IIIb; Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.
[a.k.a. ENST00000484338, B8ZZR2, Q53T08]
14) '9606.ENSP00000257663':
TMEM60 - Transmembrane protein 60.
[a.k.a. hsa:85025, AF260336, C7orf35]
15) '9606.ENSP00000336831':
PLS1 - Plastin-1; Actin-bundling protein in the absence of calcium.
[a.k.a. XP_016862115, XP_011511202.1, ENST00000483507.1]
16) '9606.ENSP00000368528':
APOO - MICOS complex subunit MIC26; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function. Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride trans [...]
[a.k.a. BAG34806.1, UPI00002124C8, BC010102]
17) '9606.ENSP00000327436':
SETD3 - Actin-histidine N-methyltransferase; Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N- methyltransferase activity and probably only catalyzes histidine methylation of actin.
[a.k.a. SET domain-containing protein 3, SETD3-204, C14orf154]
18) '9606.ENSP00000362171':
NAP1L3 - Nucleosome assembly protein 1 like 3.
[a.k.a. NAP1L3-201, 4675, NP_004529]
19) '9606.ENSP00000340507':
TRIM24 - Transcription intermediary factor 1-alpha; Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP5 [...]
[a.k.a. HPA043495, ENST00000620194, tripartite motif-containing 24]
20) '9606.ENSP00000342626':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
101 query items
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