searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000353791':

SLC6A9 - Sodium- and chloride-dependent glycine transporter 1; Terminates the action of glycine by its high affinity sodium- dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission. [a.k.a. E9PJ65, CCDS85966.1, NP_001315555]

2) '9606.ENSP00000357731':

LOR - Loricrin; Major keratinocyte cell envelope protein. [a.k.a. BC034690, P23490, AAA36181.1]

3) '9606.ENSP00000344446':

FGD6 - FYVE, RhoGEF and PH domain-containing protein 6; May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity). [a.k.a. 55785, Q9P2I5, ENST00000451107]

4) '9606.ENSP00000318902':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000362122':

TNMD - Tenomodulin; May be an angiogenesis inhibitor. [a.k.a. Chondromodulin-1-like protein, AAG28395.1, uc004efy.5]

6) '9606.ENSP00000402608':

CPS1 - Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. [a.k.a. NM_001369256.1, 1373, ENST00000619804]

7) '9606.ENSP00000368976':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000217233':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000373477':

GPX3 - Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. [a.k.a. 2R37, Q86W78, EC 1.11.1.9]

10) '9606.ENSP00000253063':

SESN2 - Sestrin-2; Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway. This stress-inducible metabolic regulator also plays a role in protection against oxidative and genotoxic stresses. May negatively regulate protein translation in response to endoplasmic reticulum stress, via TORC1. May positively regulate the transcripti [...] [a.k.a. Sestrin 2, 6N0M, SES2]

11) '9606.ENSP00000316590':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000330382':

PDGFB - Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] [a.k.a. R-HSA-9006925, PDGF subunit B, M12783]

13) '9606.ENSP00000454870':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000272519':

RALB - Ras-related protein Ral-B; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles (By similarity). Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells (By similarity). Required for suppression of apoptosis. In l [...] [a.k.a. R-HSA-162582, C9JYR1, ENSP00000393782]

15) '9606.ENSP00000326170':

RFFL - E3 ubiquitin-protein ligase rififylin; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Mediates 'Lys-48'-linked polyubiquitination of PRR5L and its subsequent proteasomal degradation thereby indirectly regulating cell migration through the mTORC2 complex. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. Negatively regulates the tumor ne [...] [a.k.a. URS00008BA36C, ENST00000268850, RFFL-205]

16) '9606.ENSP00000391668':

MTMR11 - Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. [a.k.a. AK097000, BAG53406.1, AAB36953.1]

17) '9606.ENSP00000357943':

ANXA9 - Annexin A9; Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes. Belongs to the annexin family. [a.k.a. CR536481, AAG16780.1, AF230929]

18) '9606.ENSP00000350310':

ATP2B4 - Plasma membrane calcium-transporting ATPase 4; Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. By regulating sperm cell calcium homeostasis, may play a role in sperm motility (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily. [a.k.a. ATP2B4-201, NP_001001396.1, ENSP00000350201]

19) '9606.ENSP00000447803':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000265112':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

101 query items

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