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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000354850':
OGA - Protein O-GlcNAcase; [Isoform 1]: Cleaves GlcNAc but not GalNAc from O- glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta- GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity.
[a.k.a. 5VVX, AF307332, OGA-204]
2) '9606.ENSP00000312134':
PRG2 - Eosinophil granule major basic protein; Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
[a.k.a. Q6ICT2, 5553, NP_001230174.1]
3) '9606.ENSP00000263054':
SORCS1 - Sortilin related VPS10 domain containing receptor 1; Belongs to the VPS10-related sortilin family. SORCS subfamily.
[a.k.a. AY099452, NP_001193500.1, Q8WY21]
4) '9606.ENSP00000312185':
ELMO1 - Engulfment and cell motility protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
[a.k.a. 2VSZ, ELMO1-208, XP_011513956]
5) '9606.ENSP00000370527':
RCAN1 - Calcipressin-1; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
[a.k.a. CCDS33551.1, ENST00000487990.5, CH471079]
6) '9606.ENSP00000235329':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000253159':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000348056':
UBE2I - SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity. Belongs to the ubiqu [...]
[a.k.a. ENST00000566159.1, ENST00000567074, NP_919235]
9) '9606.ENSP00000358404':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000283290':
ATG3 - Ubiquitin-like-conjugating enzyme ATG3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8- phosphatidylethanolamine conju [...]
[a.k.a. Autophagy related 3, ENST00000467275, URS00008BB75A]
11) '9606.ENSP00000231509':
NR3C1 - Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand- dependent manner which recruits the RNA helicase UPF1 and the mRNA- decapping enzyme D [...]
[a.k.a. NM_001364183, 5CBX, NP_001351111.1]
12) '9606.ENSP00000343273':
KLHL7 - Kelch-like protein 7; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
[a.k.a. UPI0000037B12, XP_006715817, XM_006715754]
13) '9606.ENSP00000382507':
UBXN2B - UBX domain-containing protein 2B; Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, r [...]
[a.k.a. NP_001071087.1, ENSP00000492780, ENSP00000382507]
14) '9606.ENSP00000320081':
DIPK2A - Divergent protein kinase domain 2A; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade; Belongs to the DIPK family.
[a.k.a. 205428, ENST00000441925, CCDS3130.1]
15) '9606.ENSP00000268711':
MED9 - Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
[a.k.a. CCDS11184.1, CCDS11184, R-HSA-556833]
16) '9606.ENSP00000240055':
NFYB - Nuclear transcription factor Y subunit beta; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors; Belongs to the NFYB/HAP3 subunit family.
[a.k.a. Nuclear transcription factor Y subunit B, P25208, 6QMQ]
17) '9606.ENSP00000295992':
PCOLCE2 - Procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
[a.k.a. URS00008B657F, NM_013363, BAG37576.1]
18) '9606.ENSP00000317955':
EEA1 - Early endosome antigen 1; Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
[a.k.a. ZFYVE2, F8VUZ7, XP_011537116.1]
19) '9606.ENSP00000258428':
REV1 - DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
[a.k.a. ENSP00000317924, HPA051036, UPI00000729BE]
20) '9606.ENSP00000296026':
CXCL3 - C-X-C motif chemokine 3; Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
[a.k.a. AAH16308.1, R-HSA-388396, R-HSA-162582]
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