searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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102 query items

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1) '9606.ENSP00000357475':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

2) '9606.ENSP00000351990':

NAE1 - NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation. [a.k.a. NM_001018159, R-HSA-8951664, 2NVU]

3) '9606.ENSP00000376436':

ETS1 - Protein C-ets-1; Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion; Belongs to the ETS family. [a.k.a. CAA32904.1, XP_011540952.1, CCDS53724]

4) '9606.ENSP00000263285':

LY9 - T-lymphocyte surface antigen Ly-9; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophil [...] [a.k.a. ENST00000368038, ENST00000325549, hly9]

5) '9606.ENSP00000361980':

PKIG - cAMP-dependent protein kinase inhibitor gamma; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains; Belongs to the PKI family. [a.k.a. NM_181805.2, UPI0000470CA0, ENST00000372889]

6) '9606.ENSP00000386959':

CAPS2 - Calcyphosin-2; Calcyphosine 2. [a.k.a. ENST00000322382, CCDS73497, NP_115995]

7) '9606.ENSP00000366863':

TBC1D4 - TBC1 domain family member 4; May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake. [a.k.a. Q68D14, 9882, AK300468]

8) '9606.ENSP00000426613':

TNIP3 - TNFAIP3-interacting protein 3; Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. [a.k.a. AK024815, NM_001244764.1, XP_016864108.1]

9) '9606.ENSP00000377854':

LHX6 - LIM/homeobox protein Lhx6; Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex (By similarity). [a.k.a. ENST00000558672, CCDS6837, NM_199160]

10) '9606.ENSP00000375894':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000425487':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000349874':

NUDT13 - Nucleoside diphosphate-linked moiety X motif 13; Nudix hydrolase 13. [a.k.a. NM_001283019, NP_056985, ENSP00000349874]

13) '9606.ENSP00000397911':

SP140L - SP140 nuclear body protein like. [a.k.a. XM_017005295.1, ENST00000458341.1, CCDS77536.1]

14) '9606.ENSP00000465776':

CCDC130 - Coiled-coil domain containing 130; Belongs to the CWC16 family. [a.k.a. NM_001320561, NP_001307498.1, CCDC130-211]

15) '9606.ENSP00000388940':

TCF12 - Transcription factor 12; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). [a.k.a. ENST00000558908.5, ENSG00000140262, NM_003205]

16) '9606.ENSP00000383715':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000398481':

CADPS2 - Calcium-dependent secretion activator 2; Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity). [a.k.a. NM_001363393.1, NP_001350326, NX_Q86UW7]

18) '9606.ENSP00000451162':

CEP128 - Centrosomal protein 128. [a.k.a. ENST00000554368.1, NM_152446, ENST00000281129]

19) '9606.ENSP00000327077':

PCM1 - Pericentriolar material 1 protein; Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. Required to anchor microtubules to the centrosome. Involved in the biogenesis of cilia. Belongs to the PCM1 family. [a.k.a. ENST00000518537, ENSG00000078674, R-HSA-69278]

20) '9606.ENSP00000216223':

IL2RB - Interleukin-2 receptor subunit beta; Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. Belongs to the type I cytokine receptor family. Type 4 subfamily. [a.k.a. R-HSA-912526, R-HSA-162582, 5M5E]

102 query items

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