searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000362201':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

2) '9606.ENSP00000395474':

SNX10 - Sorting nexin-10; Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption. [a.k.a. SNX10-206, ENST00000409367.5, AC074295]

3) '9606.ENSP00000438483':

KPNA2 - Importin subunit alpha-1; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] [a.k.a. R-HSA-388396, R-HSA-9006925, SRP1-alpha]

4) '9606.ENSP00000376505':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000354995':

ABCG1 - ATP-binding cassette sub-family G member 1; Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta- hydroxycholesterol and this transport is coupled to hydrlysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta- hydroxycholesterol ; Belongs to the ABC transporter superfamily. ABCG [...] [a.k.a. WHITE1, NM_004915.3, BAB13728.2]

6) '9606.ENSP00000466897':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

7) '9606.ENSP00000463981':

J3QR06_HUMAN - Uncharacterized protein. [a.k.a. ENST00000584948.1, AC134669, UPI000268B09D]

8) '9606.ENSP00000292303':

CCR5 - C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. [a.k.a. P51681, AIP93481.1, R-HSA-162587]

9) '9606.ENSP00000351947':

SMARCAD1 - ATP-dependent helicase 1; DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double- strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs. Required for the restoration of heterochromatin organization after replication. Acts at replication sites to facilitate the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3 'Lys-9' trimethylation (H3K9me3) and restorat [...] [a.k.a. B7Z799, AC096746, AK027490]

10) '9606.ENSP00000376436':

ETS1 - Protein C-ets-1; Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion; Belongs to the ETS family. [a.k.a. CAA32904.1, XP_011540952.1, CCDS53724]

11) '9606.ENSP00000379997':

GAPT - Protein GAPT; Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity). Belongs to the GAPT family. [a.k.a. ENST00000318469, ENST00000396776.6, ENST00000511178]

12) '9606.ENSP00000386787':

TMEM131L - Transmembrane protein 131-like; [Isoform 1]: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation. [a.k.a. ENST00000478919.1, ENST00000445960, NM_001131007]

13) '9606.ENSP00000262133':

RBL2 - Retinoblastoma-like protein 2; Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially [...] [a.k.a. XM_011523253, R-HSA-1362300, R-HSA-69278]

14) '9606.ENSP00000344218':

C1orf162 - Transmembrane protein C1orf162; Chromosome 1 open reading frame 162. [a.k.a. XP_016855812, NP_777556.1, Q8NEQ5]

15) '9606.ENSP00000425487':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000375622':

LAIR1 - Leukocyte-associated immunoglobulin-like receptor 1; Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Modulates cytokine production in CD4+ T- cells, down-regulating IL2 and IFNG production while induc [...] [a.k.a. ENST00000463489, ENSP00000393735, CR542051]

17) '9606.ENSP00000371364':

TMEM156 - Transmembrane protein 156. [a.k.a. XP_011512055, ENST00000381938, ENST00000381938.3]

18) '9606.ENSP00000247270':

EVI2A - Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor. [a.k.a. HGNC:3499, EVDA, ENST00000394756]

19) '9606.ENSP00000296859':

RAPGEF6 - Rap guanine nucleotide exchange factor 6; Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP. [a.k.a. Rap guanine nucleotide exchange factor 6, RA-GEF-2, A3KN82]

20) '9606.ENSP00000484803':

FOXP1 - Forkhead box P1. [a.k.a. BT006643, XP_006713165.1, ENST00000610810]

101 query items

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