searching ... STRING: functional protein association networks

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12.0

The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000366395':

SYVN1 - E3 ubiquitin-protein ligase synoviolin; Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER- associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Protects neurons from [...] [a.k.a. Synovial apoptosis inhibitor 1, R-HSA-901042, R-HSA-162582]

2) '9606.ENSP00000358099':

RGS10 - Regulator of G-protein signaling 10; Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein. [a.k.a. R-HSA-388396, Q6IAZ6, uc001leg.4]

3) '9606.ENSP00000381007':

NAV3 - Neuron navigator 3; May regulate IL2 production by T-cells. May be involved in neuron regeneration; Belongs to the Nav/unc-53 family. [a.k.a. XP_016875654, AAM73757.1, OMIM:611629]

4) '9606.ENSP00000247271':

OMG - Oligodendrocyte-myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. [a.k.a. LOC101927057, R-HSA-193634, R-HSA-162582]

5) '9606.ENSP00000295756':

TRAT1 - T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. [a.k.a. R-HSA-9006925, TRIM, R-HSA-162582]

6) '9606.ENSP00000365730':

STK24 - Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr [...] [a.k.a. 4U8Z, 4QO9, 3A7G]

7) '9606.ENSP00000473056':

ENSP00000473056 - Novel protein. [a.k.a. AC010646.1, ENSP00000473056, ENSG00000269095]

8) '9606.ENSP00000386163':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000280082':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000381237':

HM13 - Minor histocompatibility antigen H13; Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein. Involved in the intramembrane cleavage of the integral membrane protein PSEN1. Cleav [...] [a.k.a. E1P5L3, CCDS13182.1, CAD13132.1]

11) '9606.ENSP00000417518':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000356991':

NECTIN4 - Processed poliovirus receptor-related protein 4; Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. [a.k.a. XP_005245565.1, ENSP00000356991, nectin-4]

13) '9606.ENSP00000246515':

SLURP1 - Secreted Ly-6/uPAR-related protein 1; Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory functi [...] [a.k.a. ARS(component B)-81/S, ARS, Secreted Ly-6/uPAR-related protein 1]

14) '9606.ENSP00000361397':

NUTM2G - NUT family member 2G. [a.k.a. ENST00000335456, NTM2G_HUMAN, OTTHUMG00000020305]

15) '9606.ENSP00000306157':

IL7R - Interleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP); Belongs to the type I cytokine receptor family. Type 4 subfamily. [a.k.a. ENSG00000168685, AF043125, 3DI3]

16) '9606.ENSP00000357722':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000371212':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000300249':

MAPRE2 - Microtubule-associated protein RP/EB family member 2; May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity); Belongs to the MAPRE family. [a.k.a. NM_001256420.2, ENST00000590793, KF456373]

19) '9606.ENSP00000442682':

ADAP1 - Arf-GAP with dual PH domain-containing protein 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). [a.k.a. CCDS5318.1, 3FEH, ENSP00000413423]

20) '9606.ENSP00000312299':

FRG2C - Protein FRG2-like-2; FSHD region gene 2 family member C. [a.k.a. XP_016860978.1, uc003dpt.6, FSHD region gene 2 protein family member C]

101 query items

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