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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000367197':
SCGN - Secretagogin, EF-hand calcium binding protein.
[a.k.a. ENSP00000190668, CH471087, CAB004005]
2) '9606.ENSP00000418525':
MME - Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family.
[a.k.a. CALLA, MME-213, ENST00000462837.5]
3) '9606.ENSP00000356630':
HECA - Headcase protein homolog; May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs.
[a.k.a. NP_057301, ENST00000230165, OMIM:607977]
4) '9606.ENSP00000410964':
ERLIN1 - Erlin-1; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5- trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex ; Belongs to the band 7/mec-2 family.
[a.k.a. NP_001334786, ENSP00000266054, EAW49847.1]
5) '9606.ENSP00000403400':
CCPG1 - Cell cycle progression protein 1; Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation. Belongs to the CCPG1 family.
[a.k.a. ENST00000563171, ENST00000564663, CCDS55966.1]
6) '9606.ENSP00000296280':
MASP1 - Mannan binding lectin serine peptidase 1.
[a.k.a. AC007920, NR_033519, XP_011511292.1]
7) '9606.ENSP00000384620':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000444950':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000259053':
CD302 - CD302 antigen; Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.
[a.k.a. DCL-1, ENSG00000241399, AY314007]
10) '9606.ENSP00000477979':
NBPF9 - Neuroblastoma breakpoint family member 9; NBPF member 9; Belongs to the NBPF family.
[a.k.a. NM_001037675.3, 400818, ENST00000613595.4]
11) '9606.ENSP00000227525':
TMEM109 - Transmembrane protein 109; May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Can form voltage-gated calcium and potassium channels in vitro (By similarity).
[a.k.a. ENST00000446886, ENST00000227525, CCDS7996]
12) '9606.ENSP00000355902':
GPATCH2 - G patch domain-containing protein 2; Enhances the ATPase activity of DHX15 in vitro.
[a.k.a. Q5VYK8, ENST00000366935, CCDS73031]
13) '9606.ENSP00000383641':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
14) '9606.ENSP00000350719':
SYNE2 - Nesprin-2; Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane acti [...]
[a.k.a. Q8WXH0, Protein NUANCE, ENST00000553308.1]
15) '9606.ENSP00000444788':
TDO2 - Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
[a.k.a. 6A4I, TDO, ENSG00000151790]
16) '9606.ENSP00000255499':
RNF128 - E3 ubiquitin-protein ligase RNF128; E3 ubiquitin-protein ligase that catalyzes 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with 'Lys-48' linkages and COR1A with 'Lys-63' linkages leading to their degradation, down- regulation of these cytoslele [...]
[a.k.a. GRAIL, R-HSA-5689880, BC030951]
17) '9606.ENSP00000449535':
ACSS3 - Acyl-CoA synthetase short-chain family member 3, mitochondrial; Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Propionate is the preferred substrate. Can utilize acetate and butyrate with a much lower affinity (By similarity); Belongs to the ATP-dependent AMP-binding enzyme family.
[a.k.a. A0A0B4J1R2, Propionate--CoA ligase, R-HSA-556833]
18) '9606.ENSP00000371693':
TNFRSF19 - Tumor necrosis factor receptor superfamily member 19; Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
[a.k.a. CCDS55893.1, TNFRSF19-203, NX_Q9NS68]
19) '9606.ENSP00000382707':
IFITM3 - Interferon-induced transmembrane protein 3; IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus [...]
[a.k.a. AFF60337.1, Q53Y76, AFF60339.1]
20) '9606.ENSP00000422607':
ACSL1 - Long-chain-fatty-acid--CoA ligase 1; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs) (By similarity); Belongs to the ATP-dependent AMP-binding enzyme family.
[a.k.a. B7Z452, XP_016863376.1, XM_011531742]
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