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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000367323':
KCNAB2 - Voltage-gated potassium channel subunit beta-2; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5 [...]
[a.k.a. XM_011542322.2, CCDS55, ENST00000378097]
2) '9606.ENSP00000371194':
LSP1 - Lymphocyte-specific protein 1; May play a role in mediating neutrophil activation and chemotaxis.
[a.k.a. ENST00000311604, ENSP00000400999, BAG51753.1]
3) '9606.ENSP00000312185':
ELMO1 - Engulfment and cell motility protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
[a.k.a. 2VSZ, ELMO1-208, XP_011513956]
4) '9606.ENSP00000465039':
MAP4K1 - Mitogen-activated protein kinase kinase kinase kinase 1; Serine/threonine-protein kinase, which may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Able to autophosphorylate. Together with CLNK, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity).
[a.k.a. ENST00000587300.1, 11184, ENST00000586296]
5) '9606.ENSP00000478492':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000207549':
UNC13D - Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)- dependent secretory lysosome exocytosis in mast cells.
[a.k.a. ENST00000586930, Unc-13 homolog D, UNC13D-206]
7) '9606.ENSP00000246115':
S1PR4 - Sphingosine 1-phosphate receptor 4; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
[a.k.a. R-HSA-388396, EDG6, R-HSA-162582]
8) '9606.ENSP00000364621':
SUSD3 - Sushi domain-containing protein 3; May play a role in breast tumorigenesis by promoting estrogen-dependent cell proliferation, cell-cell interactions and migration.
[a.k.a. Sushi domain containing 3, SUSD3-203, XP_011516663.1]
9) '9606.ENSP00000337825':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000257789':
ORC3 - Origin recognition complex subunit 3; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3; Belongs to the ORC3 family.
[a.k.a. NX_Q9UBD5, ENST00000257789, R-HSA-69278]
11) '9606.ENSP00000262510':
NLRC5 - Protein NLRC5; Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms; Belongs to the NLRP family.
[a.k.a. NOD4, UPI000204A915, CLR16.1]
12) '9606.ENSP00000366956':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
13) '9606.ENSP00000377771':
SIPA1 - Signal-induced proliferation-associated protein 1; GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state. Affects cell cycle progression (By similarity).
[a.k.a. ENST00000530226.1, SPA1, XM_005274189.2]
14) '9606.ENSP00000331614':
IKZF1 - DNA-binding protein Ikaros; Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus i [...]
[a.k.a. AC124014, CCDS59055.1, ENSP00000342378]
15) '9606.ENSP00000479106':
H4C1 - H4 clustered histone 1.
[a.k.a. CH471087, AAH67496.1, R-HSA-5693565]
16) '9606.ENSP00000308717':
MRPL48 - Mitochondrial ribosomal protein L48.
[a.k.a. NM_016055.6, ENST00000314282, B4DN34]
17) '9606.ENSP00000309945':
SPNS1 - Protein spinster homolog 1; Sphingolipid transporter (By similarity). May be involved in necrotic or autophagic cell death.
[a.k.a. HSpin1, ENSP00000454360, 83985]
18) '9606.ENSP00000386787':
TMEM131L - Transmembrane protein 131-like; [Isoform 1]: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation.
[a.k.a. ENST00000478919.1, ENST00000445960, NM_001131007]
19) '9606.ENSP00000367034':
H4C3 - H4 clustered histone 3.
[a.k.a. CH471087, AAH67496.1, R-HSA-5693565]
20) '9606.ENSP00000375622':
LAIR1 - Leukocyte-associated immunoglobulin-like receptor 1; Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Modulates cytokine production in CD4+ T- cells, down-regulating IL2 and IFNG production while induc [...]
[a.k.a. ENST00000463489, ENSP00000393735, CR542051]
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