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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000369009':
BCLAF3 - BCLAF1 and THRAP3 family member 3; Belongs to the BCLAF1/THRAP3 family.
[a.k.a. ENST00000308691, XM_005274474, UPI0000458B02]
2) '9606.ENSP00000373347':
SRGAP3 - SLIT-ROBO Rho GTPase-activating protein 3; GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.
[a.k.a. UPI0000074099, ENST00000433332, NM_001033117]
3) '9606.ENSP00000222718':
HOXA2 - Homeobox protein Hox-A2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. Proboscipedia subfamily.
[a.k.a. O43364, R-HSA-5619507, EAL24227.1]
4) '9606.ENSP00000359319':
PAX2 - Paired box protein Pax-2; Transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
[a.k.a. M89470, ENST00000370296, ENST00000483202.2]
5) '9606.ENSP00000268483':
TXNL4B - Thioredoxin-like protein 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition; Belongs to the DIM1 family.
[a.k.a. NP_001135790.1, Q9NX01, 3GIX]
6) '9606.ENSP00000432651':
SMTNL1 - Smoothelin-like protein 1; Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity).
[a.k.a. ENSP00000406485, XM_005273819.3, ENST00000399154]
7) '9606.ENSP00000242208':
INHBA - Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins; Belongs to the TGF-beta family.
[a.k.a. X04447, R-HSA-1502540, 1S4Y]
8) '9606.ENSP00000230658':
ISL1 - Insulin gene enhancer protein ISL-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences. Essential for [...]
[a.k.a. ENSP00000421737, P61371, U07559]
9) '9606.ENSP00000482835':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000013807':
ERCC1 - DNA excision repair protein ERCC-1; [Isoform 1]: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4; Belongs to t [...]
[a.k.a. XM_005258635.2, NP_001974.1, NP_001356337]
11) '9606.ENSP00000307479':
ARNT2 - Aryl hydrocarbon receptor nuclear translocator 2; Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. Specifically recognizes the xenobiotic response element (XRE).
[a.k.a. ENSP00000307479, BAA20766.2, ENST00000531595]
12) '9606.ENSP00000482128':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
13) '9606.ENSP00000427114':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
14) '9606.ENSP00000371532':
VLDLR - Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
[a.k.a. UPI0000055935, ENST00000382100, HGNC:12698]
15) '9606.ENSP00000418663':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
16) '9606.ENSP00000360076':
SGIP1 - SH3-containing GRB2-like protein 3-interacting protein 1; May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
[a.k.a. XP_016858013.1, XP_006711029.1, ENST00000435165]
17) '9606.ENSP00000264712':
KIF3C - Kinesin-like protein KIF3C; Microtubule-based anterograde translocator for membranous organelles; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.
[a.k.a. ENST00000417737, KIF3C-203, ENSP00000410407]
18) '9606.ENSP00000257818':
LMO2 - Rhombotin-2; Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
[a.k.a. OMIM:180385, ENST00000257818.2, ENST00000395833]
19) '9606.ENSP00000253861':
EXOC4 - Exocyst complex component 4; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
[a.k.a. ENST00000469115, ENST00000541309, AC009358]
20) '9606.ENSP00000312734':
RAB8B - Ras-related protein Rab-8B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).
[a.k.a. Q92930, NP_057614.1, AAH20654.1]
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