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The following proteins in
Homo sapiens
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24 query items
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1) '9606.ENSP00000369042':
IPO7 - Importin-7; Functions in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm [...]
[a.k.a. 10527, UPI0001F78181, Imp7]
2) '9606.ENSP00000415968':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
3) '9606.ENSP00000372326':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000217446':
PIGU - Phosphatidylinositol glycan anchor biosynthesis class U protein; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
[a.k.a. GPI transamidase subunit, NM_080476.4, XR_001754163.1]
5) '9606.ENSP00000350071':
STRN3 - Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
[a.k.a. Q13033, HPA004636, ENSP00000451028]
6) '9606.ENSP00000334140':
KLHDC10 - Kelch domain-containing protein 10; Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C phosphatase activity on MAP3K5.
[a.k.a. CCDS5815, uc003vpj.3, UPI0001B7924B]
7) '9606.ENSP00000299138':
VPS35 - Vacuolar protein sorting-associated protein 35; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of low affinity and retromer SNX proteins may [...]
[a.k.a. AL136888, UPI00025A3008, ENST00000568642]
8) '9606.ENSP00000298510':
PRDX3 - Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
[a.k.a. B2R7Z0, ENSP00000349432, Peroxiredoxin 3]
9) '9606.ENSP00000299413':
TRIM44 - Tripartite motif-containing protein 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17. Is a negative regulator of PAX6 expression.
[a.k.a. Q96DX7, EAW68133.1, OTTHUMG00000166312]
10) '9606.ENSP00000370671':
KLHL42 - Kelch-like protein 42; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.
[a.k.a. R-HSA-8951664, KLHL42-201, XM_017019698.2]
11) '9606.ENSP00000346627':
TYW5 - tRNA wybutosine-synthesizing protein 5; tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a- amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes; Belongs to the TYW5 family.
[a.k.a. ENSP00000420024, TRNA-yW synthesizing protein 5, AK095272]
12) '9606.ENSP00000335196':
GLDN - Gliomedin shedded ectodomain; Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of [...]
[a.k.a. ENST00000537339, Q6ZMI3, URS0000EBD340]
13) '9606.ENSP00000264779':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
14) '9606.ENSP00000262995':
GAB1 - GRB2-associated-binding protein 1; Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway. Belongs to the GAB family.
[a.k.a. GAB1_HUMAN, U43885, R-HSA-1643713]
15) '9606.ENSP00000336866':
RBBP9 - Serine hydrolase RBBP9; Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1.
[a.k.a. NM_006606, ENST00000202818, XP_005260709.1]
16) '9606.ENSP00000286398':
SMC2 - Structural maintenance of chromosomes protein 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Belongs to the SMC family. SMC2 subfamily.
[a.k.a. CHEMBL4105890, ENSP00000306152, R-HSA-69278]
17) '9606.ENSP00000476499':
ZBTB8B - Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.
[a.k.a. BAC03863.1, NP_001139192.1, AK092326]
18) '9606.ENSP00000302108':
PANK1 - Pantothenate kinase 1; Plays a role in the physiological regulation of the intracellular CoA concentration; Belongs to the type II pantothenate kinase family.
[a.k.a. hsa:53354, R-HSA-196854, PANK]
19) '9606.ENSP00000241502':
FYTTD1 - UAP56-interacting factor; Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4.
[a.k.a. ENSP00000376179, CR533502, ENST00000494309]
20) '9606.ENSP00000479708':
MAL2 - Protein MAL2; Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway.
[a.k.a. AY007723, ENSP00000396088, AAH12367.1]
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