Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
101 query items
showing page 1 of 6 •
first
•
previous
•
next
•
last
1) '9606.ENSP00000370596':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
2) '9606.ENSP00000359356':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
3) '9606.ENSP00000382390':
NEURL4 - Neuralized-like protein 4; Promotes CCP110 ubiquitination and proteasome-dependent degradation. By counteracting accumulation of CP110, maintains normal centriolar homeostasis and preventing formation of ectopic microtubular organizing centers.
[a.k.a. NEUL4_HUMAN, 84461, NEURL4-209]
4) '9606.ENSP00000349860':
GFPT1 - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.
[a.k.a. Q06210, XP_016859290, 2673]
5) '9606.ENSP00000287727':
ZFYVE9 - Zinc finger FYVE domain-containing protein 9; Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
[a.k.a. R-HSA-170834, SMADIP, R-HSA-3304349]
6) '9606.ENSP00000421985':
FNIP1 - Folliculin-interacting protein 1; Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. Competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. Belongs to the FNIP family.
[a.k.a. CCDS34227, ENST00000307954, NP_001008738.2]
7) '9606.ENSP00000436786':
KMT2A - Histone-lysine N-methyltransferase 2A; Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys- 4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no [...]
[a.k.a. Q59FF2, XP_011541135.1, Lysine methyltransferase 2A]
8) '9606.ENSP00000337088':
MEN1 - Menin; Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the [...]
[a.k.a. R-HSA-170834, NM_130800.2, 6E1A]
9) '9606.ENSP00000405388':
CA10 - Carbonic anhydrase-related protein 10; Does not have a catalytic activity; Belongs to the alpha-carbonic anhydrase family.
[a.k.a. NP_064563.1, ENST00000571371, ENST00000451037.6]
10) '9606.ENSP00000320239':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
11) '9606.ENSP00000319482':
DCUN1D3 - DCN1-like protein 3; Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane. When overexpressed in transformed cells, may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar.
[a.k.a. R-HSA-8951664, Q8IWE4, R-HSA-392499]
12) '9606.ENSP00000369390':
CDK14 - Cyclin-dependent kinase 14; Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuro [...]
[a.k.a. ENSG00000058091, C9IYJ9, EAW76874.1]
13) '9606.ENSP00000327104':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
14) '9606.ENSP00000387462':
ZBTB10 - Zinc finger and BTB domain-containing protein 10; May be involved in transcriptional regulation.
[a.k.a. NP_076418.3, NM_001277145, ENSG00000205189]
15) '9606.ENSP00000240587':
TSHZ3 - Teashirt homolog 3; Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway func [...]
[a.k.a. NM_020856.4, BC127095, CAH56184.1]
16) '9606.ENSP00000378307':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
17) '9606.ENSP00000260983':
HECW2 - E3 ubiquitin-protein ligase HECW2; E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition.
[a.k.a. E3 ubiquitin-protein ligase HECW2, 57520, XM_024453021]
18) '9606.ENSP00000350364':
NEGR1 - Neuronal growth regulator 1; May be involved in cell-adhesion. May function as a trans- neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity); Belongs to the immunoglobulin superfamily. IgLON family.
[a.k.a. CAD97961.1, KILON, neuronal growth regulator 1]
19) '9606.ENSP00000295851':
ABI2 - Abl interactor 2; Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation. Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge. Contributes to the regulation of actin assembly at the tips of neuro [...]
[a.k.a. ENSP00000295851, XP_016858635.1, UPI0000E1F8D6]
20) '9606.ENSP00000370213':
CLCN4 - H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Belongs to the chloride channel (TC 2.A.49) family. ClC- 4/CLCN4 subfamily.
[a.k.a. 1183, CLC4, AK289564]
101 query items
showing page 1 of 6 •
first
•
previous
•
next
•
last
<- Back
⤓ Mapping
Continue ->